[HTML][HTML] SARS-CoV-2 variants, spike mutations and immune escape

WT Harvey, AM Carabelli, B Jackson… - Nature Reviews …, 2021 - nature.com
Although most mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …

Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021 - Am Soc Microbiol
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

Evolution of enhanced innate immune evasion by SARS-CoV-2

LG Thorne, M Bouhaddou, AK Reuschl… - Nature, 2022 - nature.com
The emergence of SARS-CoV-2 variants of concern suggests viral adaptation to enhance
human-to-human transmission,. Although much effort has focused on the characterization of …

SARS-CoV-2 evolution during treatment of chronic infection

SA Kemp, DA Collier, RP Datir, IATM Ferreira, S Gayed… - Nature, 2021 - nature.com
The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
critical for virus infection through the engagement of the human ACE2 protein and is a major …

Testing at scale during the COVID-19 pandemic

TR Mercer, M Salit - Nature Reviews Genetics, 2021 - nature.com
Assembly and publication of the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome in January 2020 enabled the immediate development of tests to detect the …

The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology

BB Oude Munnink, N Worp, DF Nieuwenhuijse… - Nature medicine, 2021 - nature.com
The current coronavirus disease 2019 (COVID-19) pandemic is the first to apply whole-
genome sequencing near to real time, with over 2 million severe acute respiratory syndrome …

Sixteen novel lineages of SARS-CoV-2 in South Africa

H Tegally, E Wilkinson, RJ Lessells, J Giandhari… - Nature medicine, 2021 - nature.com
The first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in South
Africa was identified on 5 March 2020, and by 26 March the country was in full lockdown …

Phylogenetic and phylodynamic approaches to understanding and combating the early SARS-CoV-2 pandemic

SW Attwood, SC Hill, DM Aanensen… - Nature Reviews …, 2022 - nature.com
Determining the transmissibility, prevalence and patterns of movement of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is central to our understanding …

Synthesis and systematic review of reported neonatal SARS-CoV-2 infections

R Raschetti, AJ Vivanti, C Vauloup-Fellous… - Nature …, 2020 - nature.com
A number of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections
have been reported in neonates. Here, we aim to clarify the transmission route, clinical …

Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants

AK Reuschl, LG Thorne, MVX Whelan… - Nature …, 2024 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) human adaptation resulted
in distinct lineages with enhanced transmissibility called variants of concern (VOCs) …