Ageing with HIV: Challenges and biomarkers
B Rodes, J Cadinanos, A Esteban-Cantos… - …, 2022 - thelancet.com
The antiretroviral treatment (ART) developed to control HIV infection led to a revolution in the
prognosis of people living with HIV (PLWH). PLWH underwent from suffering severe disease …
prognosis of people living with HIV (PLWH). PLWH underwent from suffering severe disease …
Monocytes in HIV and SIV infection and aging: implications for inflamm-aging and accelerated aging
ZK Wallis, KC Williams - Viruses, 2022 - mdpi.com
Before the antiretroviral therapy (ART) era, people living with HIV (PLWH) experienced
complications due to AIDS more so than aging. With ART and the extended lifespan of …
complications due to AIDS more so than aging. With ART and the extended lifespan of …
Biological ageing with HIV infection: evaluating the geroscience hypothesis
Although people with HIV are living longer, as they age they remain disproportionately
burdened with multimorbidity that is exacerbated in resource-poor settings. The geroscience …
burdened with multimorbidity that is exacerbated in resource-poor settings. The geroscience …
Central nervous system (CNS) transcriptomic correlates of human immunodeficiency virus (HIV) brain RNA load in HIV-infected individuals
PP Sanna, Y Fu, E Masliah, C Lefebvre… - Scientific reports, 2021 - nature.com
To generate new mechanistic hypotheses on the pathogenesis and disease progression of
neuroHIV and identify novel therapeutic targets to improve neuropsychological function in …
neuroHIV and identify novel therapeutic targets to improve neuropsychological function in …
Epigenome-wide epidemiologic studies of human immunodeficiency virus infection, treatment, and disease progression
Despite significant advances in the treatment and care of people with HIV (PWH), several
challenges remain in our understanding of disease pathogenesis to improve patient care …
challenges remain in our understanding of disease pathogenesis to improve patient care …
Update in human immunodeficiency virus and aging
JR Faulhaber, AW Baffoe-Bonnie… - Infectious Disease …, 2023 - id.theclinics.com
Over the last 40 years, the journey of people with human immunodefiency virus (HIV)(PWH)
has moved a long way from a near-certain mortality resulting from destruction of the immune …
has moved a long way from a near-certain mortality resulting from destruction of the immune …
Urine cell-free mitochondrial DNA as a marker of weight loss and body composition in older adults with HIV
CD Johnston, EL Siegler, MC Rice… - JAIDS Journal of …, 2021 - journals.lww.com
Background: Older adults with HIV (OAH) experience more comorbidities and geriatric
syndromes than their HIV-negative peers, perhaps because of chronic inflammation. Cell …
syndromes than their HIV-negative peers, perhaps because of chronic inflammation. Cell …
Plasma cell-free mitochondrial DNA as a marker of geriatric syndromes in older adults with HIV
CD Johnston, EL Siegler, MC Rice… - JAIDS Journal of …, 2022 - journals.lww.com
Background: Older people with HIV (PWH) experience more comorbidities and geriatric
syndromes than their HIV-negative peers, perhaps due to residual inflammation despite …
syndromes than their HIV-negative peers, perhaps due to residual inflammation despite …
Mitochondria and human immunodeficiency virus: a troubled relationship enters its fourth decade
T Hulgan, DC Samuels - Clinical Infectious Diseases, 2021 - academic.oup.com
Since antiretroviral therapy (ART) was introduced for treatment of human immunodeficiency
virus (HIV) infection, mitochondria have featured prominently in the landscape of HIV clinical …
virus (HIV) infection, mitochondria have featured prominently in the landscape of HIV clinical …
Mitochondrial DNA Profiling in A Cohort of Antiretroviral Treated HIV Patients in Lagos, Nigeria: Assessment of Long-Term Effects of cART on Life Quality of PLWH
AP Okwuraiwe, RA Ahmed, D Tajudeen… - European Journal of …, 2022 - ej-med.org
The use of combined antiretroviral therapy (cART) has turned HIV infection to a manageable
condition, significantly reducing HIV-related morbidity and mortality globally. Risk of …
condition, significantly reducing HIV-related morbidity and mortality globally. Risk of …