Advances in biosensors and diagnostic technologies using nanostructures and nanomaterials
Nanoscale materials have unique properties that make them especially useful for
biomedical diagnostic applications. Recent developments in nanoengineering have resulted …
biomedical diagnostic applications. Recent developments in nanoengineering have resulted …
Cell-based biosensors: Recent trends, challenges and future perspectives
N Gupta, V Renugopalakrishnan, D Liepmann… - Biosensors and …, 2019 - Elsevier
Existing at the interface of biology and electronics, living cells have been in use as
biorecognition elements (bioreceptors) in biosensors since the early 1970s. They are an …
biorecognition elements (bioreceptors) in biosensors since the early 1970s. They are an …
Living anisotropic structural color hydrogels for cardiotoxicity screening
D Xu, Y Wang, L Sun, Z Luo, Y Luo, Y Wang, Y Zhao - ACS nano, 2023 - ACS Publications
Environmental toxins can result in serious and fatal damage in the human heart, while the
development of a viable stratagem for assessing the effects of environmental toxins on …
development of a viable stratagem for assessing the effects of environmental toxins on …
Human-induced pluripotent stem cell-derived cardiomyocytes, 3D cardiac structures, and heart-on-a-chip as tools for drug research
K Andrysiak, J Stępniewski, J Dulak - Pflügers Archiv-European Journal of …, 2021 - Springer
Abstract Development of new drugs is of high interest for the field of cardiac and
cardiovascular diseases, which are a dominant cause of death worldwide. Before being …
cardiovascular diseases, which are a dominant cause of death worldwide. Before being …
Microengineered platforms for characterizing the contractile function of in vitro cardiac models
Emerging heart-on-a-chip platforms are promising approaches to establish cardiac
cell/tissue models in vitro for research on cardiac physiology, disease modeling and drug …
cell/tissue models in vitro for research on cardiac physiology, disease modeling and drug …
Actin-microtubule cytoskeletal interplay mediated by MRTF-A/SRF signaling promotes dilated cardiomyopathy caused by LMNA mutations
C Le Dour, M Chatzifrangkeskou, C Macquart… - Nature …, 2022 - nature.com
Mutations in the lamin A/C gene (LMNA) cause dilated cardiomyopathy associated with
increased activity of ERK1/2 in the heart. We recently showed that ERK1/2 phosphorylates …
increased activity of ERK1/2 in the heart. We recently showed that ERK1/2 phosphorylates …
Cisplatin enhances cell stiffness and decreases invasiveness rate in prostate cancer cells by actin accumulation
We focused on the biomechanical and morphological characteristics of prostate cancer cells
and their changes resulting from the effect of docetaxel, cisplatin, and long-term zinc …
and their changes resulting from the effect of docetaxel, cisplatin, and long-term zinc …
Recent advances in AFM-based biological characterization and applications at multiple levels
W Liang, H Shi, X Yang, J Wang, W Yang, H Zhang… - Soft Matter, 2020 - pubs.rsc.org
Atomic force microscopy (AFM) has found a wide range of bio-applications in the past few
decades due to its ability to measure biological samples in natural environments at a high …
decades due to its ability to measure biological samples in natural environments at a high …
Non-invasive electromechanical cell-based biosensors for improved investigation of 3D cardiac models
Cardiomyocytes (CM) placed on microelectrode array (MEA) were simultaneously probed
with cantilever from atomic force microscope (AFM) system. This electric/nanomechanical …
with cantilever from atomic force microscope (AFM) system. This electric/nanomechanical …
Human induced pluripotent stem-cell-derived cardiomyocytes as models for genetic cardiomyopathies
A Brodehl, H Ebbinghaus, MA Deutsch… - International journal of …, 2019 - mdpi.com
In the last few decades, many pathogenic or likely pathogenic genetic mutations in over
hundred different genes have been described for non-ischemic, genetic cardiomyopathies …
hundred different genes have been described for non-ischemic, genetic cardiomyopathies …