Cannabinoid receptors, endocannabinoids and the enzymes responsible for their
biosynthesis and degradation constitute the endocannabinoid system. In recent decades …

Cannabis has been used for centuries to treat seizures. Recent anecdotal reports,
accumulating animal model data, and mechanistic insights have raised interest in cannabis …

Endocannabinoids are endogenous lipid signaling mediators that participate in a variety of
physiological and pathological processes. 2-Arachidonoylglycerol (2-AG) is the most …

The endocannabinoid system is up-regulated in numerous pathophysiological states such
as inflammatory, neurodegenerative, gastrointestinal, metabolic and cardiovascular …

The endocannabinoid system is represented by a group of neuromodulatory lipids and their
receptors that are involved in a variety of physiological and pathological conditions. The …

arachidonylglycerol (2-AG) is the most abundant endocannabinoid in the central nervous
system and is elevated after brain injury. Because of its rapid hydrolysis, however, the …

Traumatic brain injury (TBI) is the leading cause of death in young adults in the United
States, but there is still no effective agent for treatment. N-arachidonoylethanolamine …

The endocannabinoid system consists of cannabinoid CB1 and CB2 receptors, of
endogenous agonists for these receptors known as 'endocannabinoids', and of processes …

Cannabis use induces a plethora of actions on the CNS via its active chemical ingredients,
the so-called phytocannabinoids. These compounds have been frequently associated with …

Cannabis sativa (Cannabis) is one of the world's most well-known, yet maligned plant
species. However, significant recent research is starting to unveil the potential of Cannabis …