Understanding and treating niemann–pick type c disease: Models matter
V Pallottini, FW Pfrieger - International Journal of Molecular Sciences, 2020 - mdpi.com
Biomedical research aims to understand the molecular mechanisms causing human
diseases and to develop curative therapies. So far, these goals have been achieved for a …
diseases and to develop curative therapies. So far, these goals have been achieved for a …
Characterization of Oxygen Nanobubbles and In Vitro Evaluation of Retinal Cells in Hypoxia
V Messerschmidt, W Ren, M Tsipursky… - … Vision Science & …, 2023 - tvst.arvojournals.org
Purpose: Vein or artery occlusion causes a hypoxic environment by preventing oxygen
delivery and diffusion to tissues. Diseases such as retinal vein occlusion, central retinal …
delivery and diffusion to tissues. Diseases such as retinal vein occlusion, central retinal …
Relation of retinal oxygen measures to electrophysiology and survival indicators after permanent, incomplete ischemia in rats
N Matei, S Leahy, S Auvazian, B Thomas… - Translational stroke …, 2020 - Springer
Studies in experimental ischemia models by permanent bilateral common carotid artery
occlusion (BCCAO) have reported reduced retinal electrophysiological function, coupled …
occlusion (BCCAO) have reported reduced retinal electrophysiological function, coupled …
Prognosis and factors related to anti-VEGF therapy in patients with retinal vein occlusion and concomitant carotid artery disease
T Yang, Y Lu, F Zeng, R Yu, C Zou, R Hu, G Jin… - Scientific Reports, 2024 - nature.com
To evaluate the prognosis and influencing factors of retinal vein occlusion (RVO) in patients
with concomitant carotid artery disease receiving anti-vascular endothelial growth factor …
with concomitant carotid artery disease receiving anti-vascular endothelial growth factor …
[HTML][HTML] Optimization of an Ischemic Retinopathy Mouse Model and the Consequences of Hypoxia in a Time-Dependent Manner
I Bosnyak, N Farkas, D Molitor, B Meresz… - International Journal of …, 2024 - mdpi.com
The retina is one of the highest metabolically active tissues with a high oxygen consumption,
so insufficient blood supply leads to visual impairment. The incidence of related conditions is …
so insufficient blood supply leads to visual impairment. The incidence of related conditions is …
Retinal oxygen delivery, metabolism, and extraction fraction during long-term bilateral common carotid artery occlusion in rats
S Leahy, S Farzad, NP Blair, M Shahidi - Scientific Reports, 2020 - nature.com
Retinal functional, biochemical, and anatomical changes have been previously reported in
long-term experimental permanent bilateral common carotid artery occlusion (BCCAO). The …
long-term experimental permanent bilateral common carotid artery occlusion (BCCAO). The …
Retinal oxygen delivery and metabolism response to hyperoxia during bilateral common carotid artery occlusion in rats
S Leahy, N Matei, NP Blair… - … Ophthalmology & Visual …, 2022 - iovs.arvojournals.org
Purpose: The purpose of the current study was to test the hypothesis that responses of total
retinal blood flow (TRBF), inner retinal oxygen delivery (DO 2), metabolism (MO 2), and …
retinal blood flow (TRBF), inner retinal oxygen delivery (DO 2), metabolism (MO 2), and …
Differential reductions in the capillary red-blood-cell flux between retina and brain under chronic global hypoperfusion
Significance It has been hypothesized that abnormal microcirculation in the retina might
predict the risk of ischemic damages in the brain. Direct comparison between the retinal and …
predict the risk of ischemic damages in the brain. Direct comparison between the retinal and …
The accumulated oxygen deficit as an indicator of the ischemic retinal insult
NP Blair, N Matei, S Leahy, M Rahimi… - Experimental eye …, 2023 - Elsevier
We here attempt to improve quantification of the ischemic retinal insult, that is, what is
imposed on the retinal tissue by ischemia, especially in experimental models of ischemia …
imposed on the retinal tissue by ischemia, especially in experimental models of ischemia …
视网膜静脉阻塞患者抗血管内皮生长因子治疗后视力差的影响因素.
杨婷婷, 刘家艳, 曾凤, 卢亚梅 - Guangdong Medical Journal, 2024 - search.ebscohost.com
目的评估视网膜静脉阻塞(RVO) 患者接受抗血管内皮生长因子(VEGF) 治疗后视力差的影响因素
. 方法以2018 年6 月至2023 年6 月期间在广州医科大学附属清远医院诊断为RVO …
. 方法以2018 年6 月至2023 年6 月期间在广州医科大学附属清远医院诊断为RVO …