Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications

JG Croissant, Y Fatieiev, A Almalik… - Advanced healthcare …, 2018 - Wiley Online Library
Predetermining the physico‐chemical properties, biosafety, and stimuli‐responsiveness of
nanomaterials in biological environments is essential for safe and effective biomedical …

Cardiac fibrosis: Myofibroblast-mediated pathological regulation and drug delivery strategies

M Liu, BL de Juan Abad, K Cheng - Advanced drug delivery reviews, 2021 - Elsevier
Cardiac fibrosis remains an unresolved problem in heart diseases. After initial injury, cardiac
fibroblasts (CFs) are activated and subsequently differentiate into myofibroblasts (myoFbs) …

Micro/nanoparticle‐augmented sonodynamic therapy (SDT): breaking the depth shallow of photoactivation

X Qian, Y Zheng, Y Chen - Advanced materials, 2016 - Wiley Online Library
The fast development of photoactivation for cancer treatment provides an efficient photo‐
therapeutic strategy for cancer treatment, but traditional photodynamic or photothermal …

[HTML][HTML] Polyethylenimine (PEI) in gene therapy: Current status and clinical applications

J Casper, SH Schenk, E Parhizkar, P Detampel… - Journal of Controlled …, 2023 - Elsevier
Polyethlyenimine (PEI) was introduced 1995 as a cationic polymer for nucleic acid delivery.
PEI and its derivatives are extensively used in basic research and as reference formulations …

Mesoporous organosilica hollow nanoparticles: synthesis and applications

Z Teng, W Li, Y Tang, A Elzatahry, G Lu… - Advanced …, 2019 - Wiley Online Library
Hollow periodic mesoporous organosilicas (PMOs) with molecularly homogeneous organic
functional groups in the inorganic pore walls are attracting more and more attention due to …

Chemistry of mesoporous organosilica in nanotechnology: molecularly organic–inorganic hybridization into frameworks

Y Chen, J Shi - Advanced Materials, 2016 - Wiley Online Library
Organic–inorganic hybrid materials aiming to combine the individual advantages of organic
and inorganic components while overcoming their intrinsic drawbacks have shown great …

[HTML][HTML] Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: evolution toward prospective theranostic approaches

J Bejarano, M Navarro-Marquez, F Morales-Zavala… - Theranostics, 2018 - ncbi.nlm.nih.gov
Cardiovascular diseases are the leading cause of death worldwide. Despite preventive
efforts, early detection of atherosclerosis, the common pathophysiological mechanism …

Response and regulation of the microenvironment based on hollow structured drug delivery systems

D Zhao, Y Wei, J Xiong, C Gao… - Advanced Functional …, 2023 - Wiley Online Library
Hollow structured materials with easily modifiable surfaces and enclosed interior spaces
have emerged as the most promising candidates in drug delivery systems (DDS). With …

Potential and applications of nanocarriers for efficient delivery of biopharmaceuticals

A Zeb, I Rana, HI Choi, CH Lee, SW Baek, CW Lim… - Pharmaceutics, 2020 - mdpi.com
During the past two decades, the clinical use of biopharmaceutical products has markedly
increased because of their obvious advantages over conventional small-molecule drug …

Emerging trends in micro-and nanoscale technologies in medicine: From basic discoveries to translation

MM Alvarez, J Aizenberg, M Analoui, AM Andrews… - ACS …, 2017 - ACS Publications
We discuss the state of the art and innovative micro-and nanoscale technologies that are
finding niches and opening up new opportunities in medicine, particularly in diagnostic and …