The renin angiotensin system as a therapeutic target in traumatic brain injury

S Villapol, ZC Janatpour, KO Affram, AJ Symes - Neurotherapeutics, 2023 - Elsevier
Traumatic brain injury (TBI) is a major public health problem, with limited pharmacological
options available beyond symptomatic relief. The renin angiotensin system (RAS) is …

A comprehensive and updated review on the applications of vesicular drug delivery systems in treatment of brain disorders: A shelter against storms

MA Rajizadeh, S Motamedy, Y Mir… - Journal of Drug Delivery …, 2023 - Elsevier
Vesicular drug delivery carriers, a subgroup of colloidal drug delivery systems (CDDS), can
be defined as highly ordered assemblies consisting of one or more concentric bilayers …

The role of inhaled estradiol and myrtenol, alone and in combination, in modulating behavioral and functional outcomes following traumatic experimental brain injury …

MA Rajizadeh, M Khaksari, MA Bejeshk… - Neurocritical Care, 2023 - Springer
Background Traumatic brain injury (TBI) is an important and growing cause of disability
worldwide, and its cognitive consequences may be particularly significant. This study …

The changes of brain edema and neurological outcome, and the probable mechanisms in diffuse traumatic brain injury induced in rats with the history of exercise

N Soltani, Z Soltani, M Khaksari, G Ebrahimi… - Cellular and molecular …, 2020 - Springer
Since no definitive treatment has been suggested for diffuse traumatic brain injury (TBI), and
also as the effect of exercise has been proven to be beneficial in neurodegenerative …

Can mesenchymal stem cells act multipotential in traumatic brain injury?

F Dehghanian, Z Soltani, M Khaksari - Journal of Molecular Neuroscience, 2020 - Springer
Traumatic brain injury (TBI), a leading cause of morbidity and mortality throughout the world,
will probably become the third cause of death in the world by the year 2020. Lack of effective …

Manifestation of renin angiotensin system modulation in traumatic brain injury

G Mirzahosseini, S Ismael, HA Ahmed, T Ishrat - Metabolic brain disease, 2021 - Springer
Traumatic brain injury (TBI) alters brain function and is a crucial public health concern
worldwide. TBI triggers the release of inflammatory mediators (cytokines) that aggravate …

Licochalcone B attenuates neuronal injury through anti-oxidant effect and enhancement of Nrf2 pathway in MCAO rat model of stroke

B Zhou, H Wang, B Zhang, L Zhang - International immunopharmacology, 2021 - Elsevier
Background Investigating anti-oxidant therapies that lead to the diminution of oxidative injury
is priority in clinical. We herein aimed to explore whether and how Licochalcone B (Lico B) …

[HTML][HTML] Losartan treatment could improve the outcome of TBI mice

J Xiong, Y Gao, X Li, K Li, Q Li, J Shen, Z Han… - Frontiers in …, 2020 - frontiersin.org
Traumatic brain injury frequently leads to serious mortality and physical disability, yet
effective treatments remains insufficient. TBI always leads to a series of secondary brain …

The effect of oral mucosal mesenchymal stem cells on pathological and Long‐Term outcomes in experimental traumatic brain injury

F Dehghanian, Z Soltani, A Farsinejad… - BioMed Research …, 2022 - Wiley Online Library
Background. Neuroprotective effects of stem cells have been shown in some neurologic
diseases. In this study, the effect of oral mucosal mesenchymal stem cells (OMSCs) on …

Interaction of estradiol and renin–angiotensin system with microRNAs-21 and-29 in renal fibrosis: focus on TGF-β/smad signaling pathway

S Rajabi, S Saberi, H Najafipour, M Askaripour… - Molecular Biology …, 2024 - Springer
Kidney fibrosis is one of the complications of chronic kidney disease (CKD (and contributes
to end-stage renal disease which requires dialysis and kidney transplantation. Several …