Medetomidine is a relatively new sedative analgesic drug that is approved for use in dogs in
Canada. It is the most potent α 2-adrenoreceptor available for clinical use in veterinary …

Abstract Alpha 2-adrenoreceptor agonists (α 2-agonists) are commonly used in small animal
anaesthesia for their potent sedative and analgesic properties, although concerns about …

The present study aimed to investigate whether dexmedetomidine (Dex) exerts
cardioprotection effect through inhibiting ferroptosis. Myocardial ischemia/reperfusion injury …

Now in its 7th edition, this popular, must-have text remains the only encyclopedic resource
for veterinary internal medical problems. The internationally acclaimed" gold standard" offers …

Aim To determine the absolute bioavailability of extravascularly administered
dexmedetomidine, a novel a2‐adrenoceptor agonist, in healthy subjects. Methods Single 2 …

Sedatives and tranquilizers play an important role in day‐to‐day veterinary practice. The use
of these medications as part of an anesthetic regimen has many advantages, including, but …

Objective To evaluate and compare the clinical effects of dexmedetomidine (DEX) and
medetomidine (MED) in cats, and their reversal with atipamezole (ATI). Study design …

Background Tracheal intubation can elicit reflex bronchoconstriction in patients with asthma
or chronic obstructive pulmonary disease, complicating mechanical ventilation and weaning …

Objective To measure the change in the minimum alveolar concentration of isoflurane
associated with three constant rate infusions of dexmedetomidine. Study design …

Resting-state functional connectivity, manifested as spontaneous synchronous activity in the
brain, has been detected by functional MRI (fMRI) across species such as humans …