Nanomedicine opens new therapeutic avenues for attacking viral diseases and for
improving treatment success rates. Nanoparticulate-based systems might change the …

Several viruses cause pulmonary infections due to their shared tropism with cells of the
respiratory tract. These respiratory problems due to viral infection become a public health …

RNA interference (RNAi) is an efficient process of posttranscriptional gene silencing. In
recent years it has been developed into a new technology in biopharmaceutical fields of …

Influenza is an important research subject around the world because of its threat to
humanity. Influenza A virus (IAV) causes seasonal epidemics and sporadic, but dangerous …

The naturally occurring structure and biological functions of RNA are correlated, which
includes hammerhead ribozymes. We proposed new variants of hammerhead ribozymes …

Despite 75 years of research into prevention and treatment of influenza, the viruses that
cause this disease continue to rank as some of the most important pathogens afflicting …

Nonstructural protein 1 (NS1) of influenza A viruses counteracts the host immune response
against the influenza viruses by not only inhibiting the nuclear export and maturation of host …

Influenza A virus genome segment 7 encodes protein M1, which is the matrix protein playing
crucial role in the virus life cycle. Any antiviral strategy that aims at reducing, in particular, the …

Influenza A virus seasonal outbreaks and occasional pandemics represent a global health
threat. The high genetic instability of this virus permits rapid escape from the host immune …

One of the hallmarks of progression of influenza virus replication is the step involving the
virus uncoating that occurs in the host cytoplasm. The BM2 ion channel protein of influenza …