Mechanisms of Chemical Carcinogenicity and Mutagenicity: A Review with Implications for
Predictive Toxicology | Chemical Reviews ACS ACS Publications C&EN CAS Find my …

Nitroaromatic compounds (NACs) are ubiquitous in the environment due to their extensive
industrial applications. The recalcitrance of NACs causes their arduous degradation …

Carcinogenicity refers to a highly toxic end point of certain chemicals, and has become an
important issue in the drug development process. In this study, three novel ensemble …

Toxicity evaluation is an important part of the preclinical safety assessment of new drugs,
which is directly related to human health and the fate of drugs. It is of importance to study …

In order to minimize expensive drug failures, is essential to determine potential activity,
toxicity and ADME problems as early as possible. In view of the large libraries of compounds …

Carcinogenicity of chemicals is a highly concerning toxicological endpoint closely
associated with human health. To implement the 3R principles of animal studies in the …

Variable selection is a procedure used to select the most important features to obtain as
much information as possible from a reduced amount of features. The selection stage is …

Carcinogenicity testing plays an essential role in identifying carcinogens in environmental
chemistry and drug development. However, it is a time-consuming and label-intensive …

Room-temperature ionic liquids (ILs) are considered green chemicals that may replace
volatile organic solvents currently used by industry. However, toxicological effects of ILs are …

Substituted polycyclic aromatic hydrocarbons (PAHs) are PAH derivatives in which
substituents replace hydrogen atoms on the aromatic benzene ring, or N/S/O atoms replace …