Age, host response, and mortality in COVID-19
VC Veiga, AB Cavalcanti - European Respiratory Journal, 2023 - Eur Respiratory Soc
Extract Increased age is a strong risk factor for mortality in patients with coronavirus disease
2019 (COVID-19)[1, 2]. Risk of death increases 1.5 times for every 10 years [1]. Among the …
2019 (COVID-19)[1, 2]. Risk of death increases 1.5 times for every 10 years [1]. Among the …
[HTML][HTML] The association of inflammatory markers with frailty and in-hospital mortality in older COVID-19 patients
ET Van Hoi, B Appelman, S Mooijaart… - Experimental …, 2024 - Elsevier
Introduction During the COVID19 pandemic, older patients hospitalized for COVID-19
exhibited an increased mortality risk compared to younger patients. While ageing is …
exhibited an increased mortality risk compared to younger patients. While ageing is …
Viral Pneumonia: From Influenza to COVID-19
C Cilloniz, G Dy-Agra… - … in Respiratory and …, 2024 - thieme-connect.com
Respiratory viruses are increasingly recognized as a cause of community-acquired
pneumonia (CAP). The implementation of new diagnostic technologies has facilitated their …
pneumonia (CAP). The implementation of new diagnostic technologies has facilitated their …
Host response changes and their association with mortality in COVID-19 patients with lymphopenia
EHA Michels, B Appelman, J de Brabander… - American journal of …, 2024 - atsjournals.org
Rationale: Lymphopenia in coronavirus disease (COVID-19) is associated with increased
mortality. Objectives: To explore the association between lymphopenia, host response …
mortality. Objectives: To explore the association between lymphopenia, host response …
Aging is associated with an insufficient early inflammatory response of lung endothelial cells in SARS-CoV-2 infection
Advanced age is associated with an increased susceptibility to Coronavirus Disease
(COVID)-19 and more severe outcomes, although the underlying mechanisms are …
(COVID)-19 and more severe outcomes, although the underlying mechanisms are …
Proteomic profiling of neutrophils and plasma in community-acquired pneumonia reveals crucial proteins in diverse biological pathways linked to clinical outcome
EHA Michels, O Chouchane, J De Brabander… - Frontiers in …, 2024 - frontiersin.org
Introduction Neutrophils play a dichotomous role in community-acquired pneumonia (CAP),
providing protection and potentially causing damage. Existing research on neutrophil …
providing protection and potentially causing damage. Existing research on neutrophil …
Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19
The COVID-19 pandemic has significantly impacted global health, especially in vulnerable
populations like kidney transplant recipients (KTRs). Recently, mass spectrometry-based …
populations like kidney transplant recipients (KTRs). Recently, mass spectrometry-based …
[HTML][HTML] Biomarker Analysis Provides Evidence for Host Response Homogeneity in Patients With COVID-19
RBE van Amstel, EHA Michels, B Appelman… - CHEST Critical …, 2024 - Elsevier
Background The exploration of subphenotypes in hospitalized patients with COVID-19 has
garnered substantial attention. Most existing studies operate under the assumption of …
garnered substantial attention. Most existing studies operate under the assumption of …
Predictors of SARS-CoV-2 Infection and Severe and Lethal COVID-19 after Three Years of Follow-Up: A Population-Wide Study
In this cohort study, the general population of an Italian Province was followed for three
years after the start of the pandemic, in order to identify the predictors of SARS-CoV-2 …
years after the start of the pandemic, in order to identify the predictors of SARS-CoV-2 …
Determination of Oxidative Stress and Copeptin Levels of COVID-19 According to the Clinical Course.
Objective COVID-19, caused by the novel coronavirus SARS-CoV-2, is characterized by
hyperinflammation, which can trigger oxidative stress. At the same time, COVID-19 is …
hyperinflammation, which can trigger oxidative stress. At the same time, COVID-19 is …