Targeting Farnesoid X Receptor in Tumor and the Tumor Microenvironment: Implication for Therapy

M Nenkov, Y Shi, Y Ma, N Gaßler, Y Chen - International journal of …, 2023 - mdpi.com
The farnesoid-X receptor (FXR), a member of the nuclear hormone receptor superfamily, can
be activated by bile acids (BAs). BAs binding to FXR activates BA signaling which is …

[HTML][HTML] Flow cytometry in acute myeloid leukemia and detection of minimal residual disease

Q Cai, H Lan, D Yi, B Xian, L Zidan, J Li, Z Liao - Clinica Chimica Acta, 2024 - Elsevier
Acute myeloid leukemia (AML) is a common type of acute leukemia (AL), belonging to
malignant tumors of the hematopoietic system with the characteristics of rapid disease …

Targeting Transient Receptor Potential Melastatin‐2 (TRPM2) Enhances Therapeutic Efficacy of Third Generation EGFR Inhibitors against EGFR Mutant Lung Cancer

Z Chen, KA Vallega, VK Boda, Z Quan… - Advanced …, 2024 - Wiley Online Library
There is an urgent need to fully understand the biology of third generation EGFR‐tyrosine
kinase inhibitors (EGFR‐TKIs), particularly osimertinib, and to develop mechanism‐driven …