• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Answer questions and earn CME/CNE The concept of frailty has become increasingly
recognized as one of the most important issues in health care and health outcomes and is of …

Importance Several studies now provide evidence of ketamine hydrochloride's ability to
produce rapid and robust antidepressant effects in patients with mood and anxiety disorders …

Abstract The American Society of Regional Anesthesia and Pain Medicine's Third Practice
Advisory on local anesthetic systemic toxicity is an interim update from its 2010 advisory …

Chronic diseases are major killers in the modern era. Physical inactivity is a primary cause
of most chronic diseases. The initial third of the article considers: activity and prevention …

Background This section of the guidelines is intended to provide an evidence-based
approach to the preoperative physiologic assessment of a patient being considered for …

Neurologic injury associated with regional anesthetic or pain medicine procedures is
extremely rare. The Second American Society of Regional Anesthesia and Pain Medicine …

Exercise testing remains a remarkably durable and versa-tile tool that provides valuable
diagnostic and prognostic information regarding patients with cardiovascular and pulmonary …

BACKGROUND: Preoperative risk assessment is important yet inexact in older patients
because physiologic reserves are difficult to measure. Frailty is thought to estimate …

The National High Blood Pressure Education Program presents the complete Seventh
Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment …