[HTML][HTML] Dissecting the functional organization of the C. elegans serotonergic system at whole-brain scale

U Dag, I Nwabudike, D Kang, MA Gomes, J Kim… - Cell, 2023 - cell.com
Serotonin influences many aspects of animal behavior. But how serotonin acts on its diverse
receptors across the brain to modulate global activity and behavior is unknown. Here, we …

Legacies of salient environmental experiences—insights from chemosensation

BG Dias - Chemical Senses, 2024 - academic.oup.com
Evidence for parental environments profoundly influencing the physiology, biology, and
neurobiology of future generations has been accumulating in the literature. Recent efforts to …

[HTML][HTML] Neuroendocrine gene expression coupling of interoceptive bacterial food cues to foraging behavior of C. elegans

SA Boor, JD Meisel, DH Kim - Elife, 2024 - elifesciences.org
Animal internal state is modulated by nutrient intake, resulting in behavioral responses to
changing food conditions. The neural mechanisms by which internal states are generated …

Functional imaging and quantification of multineuronal olfactory responses in C. elegans

A Lin, S Qin, H Casademunt, M Wu, W Hung… - Science …, 2023 - science.org
Many animals perceive odorant molecules by collecting information from ensembles of
olfactory neurons, where each neuron uses receptors that are tuned to recognize certain …

[HTML][HTML] ADAR-mediated regulation of PQM-1 expression in neurons impacts gene expression throughout C. elegans and regulates survival from hypoxia

A Mahapatra, A Dhakal, A Noguchi, P Vadlamani… - PLoS …, 2023 - journals.plos.org
The ability to alter gene expression programs in response to changes in environmental
conditions is central to the ability of an organism to thrive. For most organisms, the nervous …

Developmental history modulates adult olfactory behavioral preferences via regulation of chemoreceptor expression in Caenorhabditiselegans

T Kyani-Rogers, A Philbrook, IG McLachlan… - Genetics, 2022 - academic.oup.com
Developmental experiences play critical roles in shaping adult physiology and behavior. We
and others previously showed that adult Caenorhabditis elegans which transiently …

[HTML][HTML] Pheromone-based communication influences the production of somatic extracellular vesicles in C. elegans

A Szczepańska, K Olek, K Kołodziejska, J Yu… - Nature …, 2024 - nature.com
Extracellular vesicles (EVs) are integral to numerous biological processes, yet it is unclear
how environmental factors or interactions among individuals within a population affect EV …

[HTML][HTML] Icariin Improves Stress Resistance and Extends Lifespan in Caenorhabditis elegans through hsf-1 and daf-2-Driven Hormesis

MN Todorova, MS Savova, LV Mihaylova… - International Journal of …, 2023 - mdpi.com
Aging presents an increasingly significant challenge globally, driven by the growing
proportion of individuals aged 60 and older. Currently, there is substantial research interest …

[HTML][HTML] Dietary E. coli promotes age-dependent chemotaxis decline in C. elegans

N Suryawinata, R Yokosawa, KHC Tan, AL Lai… - Scientific Reports, 2024 - nature.com
An animal's ability to sense odors declines during aging, and its olfactory drive is tuned by
internal states such as satiety. However, whether internal states modulate an age …

[HTML][HTML] Neuroendocrine Coupling of Interoceptive Bacteria-Derived Cues to Foraging Behavior in C. elegans

SA Boor, JD Meisel, DH Kim - eLife, 2023 - elifesciences.org
Animal internal state is modulated by nutrient intake, resulting in behavioral responses to
changing food conditions. DAF-7 is a neuroendocrine TGF-beta ligand that regulates …