Hippocampus and its involvement in Alzheimer's disease: a review

YL Rao, B Ganaraja, BV Murlimanju, T Joy… - 3 Biotech, 2022 - Springer
Hippocampus is the significant component of the limbic lobe, which is further subdivided into
the dentate gyrus and parts of Cornu Ammonis. It is the crucial region for learning and …

Insulin and insulin resistance in Alzheimer's disease

A Sędzikowska, L Szablewski - International journal of molecular sciences, 2021 - mdpi.com
Insulin plays a range of roles as an anabolic hormone in peripheral tissues. It regulates
glucose metabolism, stimulates glucose transport into cells and suppresses hepatic glucose …

Defective mitophagy in Alzheimer's disease

JA Pradeepkiran, PH Reddy - Ageing Research Reviews, 2020 - Elsevier
Alzheimer's disease (AD) is a progressive, mental illness without cure. Several years of
intense research on postmortem AD brains, cell and mouse models of AD have revealed …

Oxidative stress, synaptic dysfunction, and Alzheimer's disease

E Tönnies, E Trushina - Journal of Alzheimer's Disease, 2017 - content.iospress.com
Alzheimer's disease (AD) is a devastating neurodegenerative disorder without a cure. Most
AD cases are sporadic where age represents the greatest risk factor. Lack of understanding …

[HTML][HTML] Mitochondrial dysfunction and oxidative stress in metabolic disorders—A step towards mitochondria based therapeutic strategies

JS Bhatti, GK Bhatti, PH Reddy - … et Biophysica Acta (BBA)-Molecular Basis …, 2017 - Elsevier
Mitochondria are the powerhouses of the cell and are involved in essential functions of the
cell, including ATP production, intracellular Ca 2+ regulation, reactive oxygen species …

Diverse roles of mitochondria in immune responses: novel insights into immuno-metabolism

A Angajala, S Lim, JB Phillips, JH Kim, C Yates… - Frontiers in …, 2018 - frontiersin.org
Lack of immune system cells or impairment in differentiation of immune cells is the basis for
many chronic diseases. Metabolic changes could be the root cause for this immune cell …

Neuroprotective mechanisms of resveratrol in Alzheimer's disease: role of SIRT1

BAQ Gomes, JPB Silva, CFR Romeiro… - Oxidative medicine …, 2018 - Wiley Online Library
Alzheimer's disease (AD) is a progressive and neurodegenerative disorder of the cortex and
hippocampus, which eventually leads to cognitive impairment. Although the etiology of AD …

[HTML][HTML] Is Alzheimer's disease a type 3 diabetes? A critical appraisal

R Kandimalla, V Thirumala, PH Reddy - Biochimica et Biophysica Acta …, 2017 - Elsevier
Recently researchers proposed the term 'Type-3-Diabetes' for Alzheimer's disease (ad)
because of the shared molecular and cellular features among Type-1-Diabetes, Type-2 …

Defective mitophagy and synaptic degeneration in Alzheimer's disease: Focus on aging, mitochondria and synapse

H Morton, S Kshirsagar, E Orlov, LE Bunquin… - Free Radical Biology …, 2021 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and multiple cognitive impairments. AD is marked by multiple cellular changes …

Synaptic basis of Alzheimer's disease: Focus on synaptic amyloid beta, P-tau and mitochondria

A John, PH Reddy - Ageing research reviews, 2021 - Elsevier
Alzheimer's disease (AD) is a progressive and synaptic failure disease. Despite the many
years of research, AD still harbors many secrets. As more of the world's population grows …