High WSS or low WSS? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture: toward a unifying hypothesis
Increasing detection of unruptured intracranial aneurysms, catastrophic outcomes from
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …
Review of cerebral aneurysm formation, growth, and rupture
Figure. Cerebral aneurysm (CA) formation and rupture. Aneurysm formation is initiated by
hemodynamically triggered endothelial dysfunction. An inflammatory response implicating …
hemodynamically triggered endothelial dysfunction. An inflammatory response implicating …
Guidelines for the management of patients with unruptured intracranial aneurysms: a guideline for healthcare professionals from the American Heart Association …
BG Thompson, RD Brown Jr, S Amin-Hanjani… - Stroke, 2015 - Am Heart Assoc
Purpose—The aim of this updated statement is to provide comprehensive and evidence-
based recommendations for management of patients with unruptured intracranial …
based recommendations for management of patients with unruptured intracranial …
Hemodynamic–morphologic discriminants for intracranial aneurysm rupture
Background and Purpose—The purpose of this study was to identify significant
morphological and hemodynamic parameters that discriminate intracranial aneurysm …
morphological and hemodynamic parameters that discriminate intracranial aneurysm …
Saccular intracranial aneurysm: pathology and mechanisms
J Frösen, R Tulamo, A Paetau, E Laaksamo… - Acta …, 2012 - Springer
Saccular intracranial aneurysms (sIA) are pouch-like pathological dilatations of intracranial
arteries that develop when the cerebral artery wall becomes too weak to resist …
arteries that develop when the cerebral artery wall becomes too weak to resist …
Quantitative characterization of the hemodynamic environment in ruptured and unruptured brain aneurysms
BACKGROUND AND PURPOSE: Hemodynamics are thought to play an important role in
the mechanisms of aneurysm pathogenesis, progression, and rupture. The purpose of this …
the mechanisms of aneurysm pathogenesis, progression, and rupture. The purpose of this …
Role of hemodynamic shear stress in cardiovascular disease
E Cecchi, C Giglioli, S Valente, C Lazzeri, GF Gensini… - Atherosclerosis, 2011 - Elsevier
Atherosclerosis is the main cause of morbidity and mortality in the Western world.
Inflammation and blood flow alterations are new markers emerging as possible …
Inflammation and blood flow alterations are new markers emerging as possible …
Morphology parameters for intracranial aneurysm rupture risk assessment
OBJECTIVE: The aim of this study is to identify image-based morphological parameters that
correlate with human intracranial aneurysm (IA) rupture. METHODS: For 45 patients with …
correlate with human intracranial aneurysm (IA) rupture. METHODS: For 45 patients with …
Association of hemodynamic characteristics and cerebral aneurysm rupture
BACKGROUND AND PURPOSE: Hemodynamic factors are thought to play an important
role in the initiation, growth, and rupture of cerebral aneurysms. This report describes a …
role in the initiation, growth, and rupture of cerebral aneurysms. This report describes a …
Patient-specific modeling of cardiovascular mechanics
CA Taylor, CA Figueroa - Annual review of biomedical …, 2009 - annualreviews.org
Advances in numerical methods and three-dimensional imaging techniques have enabled
the quantification of cardiovascular mechanics in subject-specific anatomic and physiologic …
the quantification of cardiovascular mechanics in subject-specific anatomic and physiologic …