[HTML][HTML] A review of neutrophil extracellular traps (NETs) in disease: potential anti-NETs therapeutics
V Mutua, LJ Gershwin - Clinical reviews in allergy & immunology, 2021 - Springer
Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …
Cellular mechanisms of NETosis
Neutrophils are critical to innate immunity, including host defense against bacterial and
fungal infections. They achieve their host defense role by phagocytosing pathogens …
fungal infections. They achieve their host defense role by phagocytosing pathogens …
[HTML][HTML] Neutrophil extracellular traps (NETs) take the central stage in driving autoimmune responses
Following fifteen years of research, neutrophil extracellular traps (NETs) are widely reported
in a large range of inflammatory infectious and non-infectious diseases. Cumulating …
in a large range of inflammatory infectious and non-infectious diseases. Cumulating …
[HTML][HTML] Oxidized mitochondrial DNA induces gasdermin D oligomerization in systemic lupus erythematosus
N Miao, Z Wang, Q Wang, H Xie, N Yang… - Nature …, 2023 - nature.com
Although extracellular DNA is known to form immune complexes (ICs) with autoantibodies in
systemic lupus erythematosus (SLE), the mechanisms leading to the release of DNA from …
systemic lupus erythematosus (SLE), the mechanisms leading to the release of DNA from …
Neutrophil extracellular traps in chronic lung disease: implications for pathogenesis and therapy
HR Keir, JD Chalmers - European Respiratory Review, 2022 - Eur Respiratory Soc
Neutrophilic inflammation has a key role in the pathophysiology of multiple chronic lung
diseases. The formation of neutrophil extracellular traps (NETs) has emerged as a key …
diseases. The formation of neutrophil extracellular traps (NETs) has emerged as a key …
[HTML][HTML] Neutrophils in psoriasis
Neutrophils are the most abundant innate immune cells. The pathogenic roles of neutrophils
are related to chronic inflammation and autoimmune diseases. Psoriasis is a chronic …
are related to chronic inflammation and autoimmune diseases. Psoriasis is a chronic …
[HTML][HTML] Neutrophils: need for standardized nomenclature
E McKenna, AU Mhaonaigh, R Wubben… - Frontiers in …, 2021 - frontiersin.org
Neutrophils are the most abundant innate immune cell with critical anti-microbial functions.
Since the discovery of granulocytes at the end of the nineteenth century, the cells have been …
Since the discovery of granulocytes at the end of the nineteenth century, the cells have been …
Neutrophil extracellular traps contribute to liver damage and increase defective low-density neutrophils in alcohol-associated hepatitis
Background & Aims In alcohol-associated hepatitis (AH), inflammation and neutrophil counts
correlate with poor clinical outcomes. Here, we investigated how neutrophils contribute to …
correlate with poor clinical outcomes. Here, we investigated how neutrophils contribute to …
[HTML][HTML] Neutrophil extracellular traps and cardiovascular diseases: an update
Neutrophil extracellular traps (NETs) are formed by decondensed chromatin, histones, and
neutrophil granular proteins and have a role in entrapping microbial pathogens. NETs …
neutrophil granular proteins and have a role in entrapping microbial pathogens. NETs …
[HTML][HTML] Insights into immunothrombosis: the interplay among neutrophil extracellular trap, von Willebrand factor, and ADAMTS13
J Yang, Z Wu, Q Long, J Huang, T Hong… - Frontiers in …, 2020 - frontiersin.org
Both neutrophil extracellular traps (NETs) and von Willebrand factor (VWF) are essential for
thrombosis and inflammation. During these processes, a complex series of events, including …
thrombosis and inflammation. During these processes, a complex series of events, including …