Challenges in the clinical implementation of precision medicine companion diagnostics
P Keeling, J Clark, S Finucane - Expert review of molecular …, 2020 - Taylor & Francis
Introduction The pace of biomarker discovery has increased exponentially over the last few
years, ushering in an era of precision medicine (PM) with a growing arsenal of treatments …
years, ushering in an era of precision medicine (PM) with a growing arsenal of treatments …
Economic evaluation of pharmacogenomics: a value-based approach to pragmatic decision making in the face of complexity
Evidence of the value of pharmacogenomic testing is needed to inform policymakers and
clinicians for decision making related to adoption and coverage, and to facilitate …
clinicians for decision making related to adoption and coverage, and to facilitate …
Delivering the precision oncology paradigm: reduced R&D costs and greater return on investment through a companion diagnostic informed precision oncology …
RH Henderson, D French, E Stewart, D Smart… - … of Pharmaceutical Policy …, 2023 - Springer
Background Precision oncology medicines represent a paradigm shift compared to non-
precision oncology medicines in cancer therapy, in some situations delivering more clinical …
precision oncology medicines in cancer therapy, in some situations delivering more clinical …
International consortium for personalized medicine: an international survey about the future of personalized medicine
J Venne, U Busshoff, S Poschadel… - Personalized …, 2020 - Taylor & Francis
Aim: The ICPerMed, international initiative promoting personalized medicine, has realized a
survey among a group of experts, to define a common vision for the deployment of …
survey among a group of experts, to define a common vision for the deployment of …
P2P cloud manufacturing based on a customized business model: An exploratory study
To overcome the problems of long production cycle and high cost in the product
manufacturing process, a P2P (platform to platform) cloud manufacturing method based on a …
manufacturing process, a P2P (platform to platform) cloud manufacturing method based on a …
Development and pilot-test of blockchain-based MyHealthData platform
The concept of MyData emerged as a paradigm shift in personal data management and the
process of seeking to transform the current organization-centered system. MyData enables …
process of seeking to transform the current organization-centered system. MyData enables …
[HTML][HTML] Towards a systems approach for chronic diseases, based on health state modeling
M Rebhan - F1000Research, 2017 - ncbi.nlm.nih.gov
Rising pressure from chronic diseases means that we need to learn how to deal with
challenges at a different level, including the use of systems approaches that better connect …
challenges at a different level, including the use of systems approaches that better connect …
Multiomics medicine in oncology: assessing effectiveness, cost–effectiveness and future research priorities for the molecularly unique individual
The development of genomic technologies has ushered in the era of pharmacogenomics.
However, discoveries and clinical use of targeted therapies are still in their infancy. A focus …
However, discoveries and clinical use of targeted therapies are still in their infancy. A focus …
Pharmacogenomic challenges in cardiovascular diseases: examples of drugs and considerations for future integration in clinical practice
J Chatelin, MG Stathopoulou… - Current …, 2017 - ingentaconnect.com
Introduction: Even if cardiovascular disease (CVD) drugs are supported by high level proofs,
the results of CVD treatment present great disparities: there are still patients dying with …
the results of CVD treatment present great disparities: there are still patients dying with …
Economic viability of stratified medicine concepts: an investor perspective on drivers and conditions that favour using stratified medicine approaches in a cost …
HJ Fugel, M Nuijten, M Postma - New biotechnology, 2016 - Elsevier
Abstract Rationale Stratified Medicine (SM) is becoming a natural result of advances in
biomedical science and a promising path for the innovation-based biopharmaceutical …
biomedical science and a promising path for the innovation-based biopharmaceutical …