Cross-talk between the tumor microenvironment (TME) and cancer cells plays an important
role in acquired drug resistance to epidermal growth factor receptor tyrosine kinase …

Simple Summary Alterations of cellular metabolism and bioenergetics, oxidative stress, and
intracellular reactive oxygen species (ROS) levels are hallmarks of cancer development …

Kidney cancer is the seventh leading cause of cancer in the world, and its incidence is on
the rise. Renal cell carcinoma (RCC) is the most common form and is a heterogeneous …

Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a malignant disease with a poor
prognosis. One prominent aspect of PDAC that contributes to its aggressive behavior is its …

Mitochondrial dysfunction is common in cancer and the mitochondrial electron transport
chain is often affected in carcinogenesis. To date, little is known about the expression of the …

Abstract N6‐Methyladenosine (m6A) is the most common modification of messenger RNA
(mRNA) in mammals. It critically influences RNA metabolism and plays an essential role in …

Fibroblast growth factor 21 (FGF21) is a hormone-like member of the FGF family that is
associated with cell death in atherosclerosis. However, its underlying mechanisms remain …

A large proportion of the heritability of pancreatic cancer risk remains elusive, and the
contribution of specific mRNA splicing events to pancreatic cancer susceptibility has not …

Introduction Mitochondrial dysfunction is common in cancer, and the mitochondrial electron
transport chain is often affected in carcinogenesis. So far, little is known about the …

Mitochondria are energetic and dynamic organelles with a crucial role in bioenergetics,
metabolism, and signaling. Mitochondrial proteins, encoded by both nuclear and …