The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Regulation of EMT in colorectal cancer: a culprit in metastasis

T Vu, PK Datta - Cancers, 2017 - mdpi.com
Epithelial to mesenchymal transition (EMT) is a process during which cells lose their
epithelial characteristics, for instance cell polarity and cell–cell contact, and gain …

[HTML][HTML] The global phosphorylation landscape of SARS-CoV-2 infection

M Bouhaddou, D Memon, B Meyer, KM White… - Cell, 2020 - cell.com
The causative agent of the coronavirus disease 2019 (COVID-19) pandemic, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed …

Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia

UC Eze, A Bhaduri, M Haeussler, TJ Nowakowski… - Nature …, 2021 - nature.com
The human cortex comprises diverse cell types that emerge from an initially uniform
neuroepithelium that gives rise to radial glia, the neural stem cells of the cortex. To …

Regulation of energy metabolism by long-chain fatty acids

MT Nakamura, BE Yudell, JJ Loor - Progress in lipid research, 2014 - Elsevier
In mammals, excess energy is stored primarily as triglycerides, which are mobilized when
energy demands arise. This review mainly focuses on the role of long chain fatty acids …

Building muscle: molecular regulation of myogenesis

CF Bentzinger, YX Wang… - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
The genesis of skeletal muscle during embryonic development and postnatal life serves as a
paradigm for stem and progenitor cell maintenance, lineage specification, and terminal …

Single-nucleus RNA-seq and FISH identify coordinated transcriptional activity in mammalian myofibers

M Dos Santos, S Backer, B Saintpierre, B Izac… - Nature …, 2020 - nature.com
Skeletal muscle fibers are large syncytia but it is currently unknown whether gene
expression is coordinately regulated in their numerous nuclei. Here we show by snRNA-seq …

Nrf2 for cardiac protection: pharmacological options against oxidative stress

QM Chen - Trends in Pharmacological Sciences, 2021 - cell.com
Myocardial ischemia or reperfusion increases the generation of reactive oxygen species
(ROS) from damaged mitochondria, NADPH oxidases, xanthine oxidase, and inflammation …

Analysis of the coding genome of diffuse large B-cell lymphoma

L Pasqualucci, V Trifonov, G Fabbri, J Ma, D Rossi… - Nature …, 2011 - nature.com
Diffuse large B-cell lymphoma (DLBCL) is the most common form of human lymphoma.
Although a number of structural alterations have been associated with the pathogenesis of …

Cardiac-specific miRNA in cardiogenesis, heart function, and cardiac pathology (with focus on myocardial infarction)

DA Chistiakov, AN Orekhov, YV Bobryshev - Journal of molecular and …, 2016 - Elsevier
Abstract Cardiac miRNAs (miR-1, miR133a, miR-208a/b, and miR-499) are abundantly
expressed in the myocardium. They play a central role in cardiogenesis, heart function and …