A promising cell-therapy approach for heart failure aims at differentiating human pluripotent
stem cells (hPSCs) into functional cardiomyocytes (CMs) in vitro to replace the disease …

Anchorage-dependent cells are of great interest for various biotechnological applications.(i)
They represent a formidable production means of viruses for vaccination purposes at very …

The immature phenotype of human pluripotent stem cell derived cardiomyocytes (hPSC-
CMs) constrains their potential in cell therapy and drug testing. In this study, we report that …

To harness the full potential of human pluripotent stem cells (hPSCs) we combined
instrumented stirred tank bioreactor (STBR) technology with the power of in silico process …

Abstract Three‐dimensional (3D) cultures of human pluripotent stem cell derived
cardiomyocytes (hPSC‐CMs) hold great promise for drug discovery, providing a better …

Hypoxia‐mimetic agents are new potential tools in MSC priming instead of hypoxia
incubators or chambers. Several pharmaceutical/chemical hypoxia‐mimetic agents can be …

Aiming at clinical translation, robust directed differentiation of human pluripotent stem cells
(hPSCs), preferentially in chemically defined conditions, is a key requirement. Here …

Human pluripotent stem cells (PSCs) represent an attractive source of cardiomyocytes with
potential applications including disease modeling, drug discovery and safety screening, and …

Recent advances in the generation of cardiomyocytes (CMs) from human pluripotent stem
cells (hPSCs), in conjunction with the promising outcomes from preclinical and clinical …

Human induced pluripotent stem cells (hiPSC) are attractive tools for drug screening and
disease modeling and promising candidates for cell therapy applications. However, to …