Thalassaemia is a diverse group of genetic disorders with a worldwide distribution affecting
globin chain synthesis. The pathogenesis of thalassaemia lies in the unbalanced globin …

Inherited haemoglobin disorders, including thalassaemia and sickle-cell disease, are the
most common monogenic diseases worldwide. Several clinical forms of α-thalassaemia and …

β-Thalassemias Defective synthesis of the β-globin chain causes recessively inherited
disorders characterized by inadequate hemoglobin production and chronic anemia …

Background Patients with non-transfusion-dependent thalassaemia (NTDT), although they
do not require regular blood transfusions for survival, can still accrue a heavy burden of …

Over the past decade, our knowledge of the clinical diagnosis and management of
thalassemia has progressed extensively. In recent years, the most critical change in clinical …

Adrenal myelolipomas are benign, lipomatous tumours with elements of myeloid cells, most
of which present as adrenal incidentalomas and comprise 3· 3–6· 5% of all adrenal masses …

Abstract β-thalassemia is a hereditary disorder with limited approved treatment options;
patients experience anemia and its complications, including iron overload. The study aim …

Hemoglobinopathies are among the most common monogenic diseases worldwide.
Approximately 1–5% of the global population are carriers for a genetic thalassemia …

Thalassemia syndromes are among the most serious and common genetic conditions. They
are indigenous in a wide but specific geographical area. However, through migration they …

The treatment landscape for patients with β‐thalassemia is witnessing a swift evolution, yet
several unmet needs continue to persist. Patients with transfusion‐dependent β …