Regulation of stress response on the hypothalamic-pituitary-gonadal axis via gonadotropin-inhibitory hormone

YL Son, T Ubuka, K Tsutsui - Frontiers in Neuroendocrinology, 2022 - Elsevier
Under stressful condition, reproductive function is impaired due to the activation of various
components of the hypothalamic–pituitaryadrenal (HPA) axis, which can suppress the …

Origin and evolution of the neuroendocrine control of reproduction in vertebrates, with special focus on genome and gene duplications

S Dufour, B Quérat, H Tostivint… - Physiological …, 2020 - journals.physiology.org
In humans, as in the other mammals, the neuroendocrine control of reproduction is ensured
by the brain-pituitary gonadotropic axis. Multiple internal and environmental cues are …

[HTML][HTML] SIFamide translates hunger signals into appetitive and feeding behavior in Drosophila

C Martelli, U Pech, S Kobbenbring, D Pauls, B Bahl… - Cell reports, 2017 - cell.com
Animal behavior is, on the one hand, controlled by neuronal circuits that integrate external
sensory stimuli and induce appropriate motor responses. On the other hand, stimulus …

Molecular, cellular, morphological, physiological and behavioral aspects of gonadotropin-inhibitory hormone

T Ubuka, YL Son, K Tsutsui - General and comparative endocrinology, 2016 - Elsevier
Gonadotropin-inhibitory hormone (GnIH) is a hypothalamic neuropeptide that was isolated
from the brains of Japanese quail in 2000, which inhibited luteinizing hormone release from …

Gonadotropin-inhibitory hormone (GnIH): A new key neurohormone controlling reproductive physiology and behavior

K Tsutsui, T Ubuka - Frontiers in Neuroendocrinology, 2021 - Elsevier
The discovery of novel neurohormones is important for the advancement of
neuroendocrinology. In early 1970s, gonadotropin-releasing hormone (GnRH), a …

[HTML][HTML] The role of adiponectin in renal physiology and development of albuminuria

GA Christou, DN Kiortsis - Journal of Endocrinology, 2014 - joe.bioscientifica.com
Adiponectin is secreted by the adipose tissue and is downregulated in states of obesity and
insulin resistance. There is a growing body of evidence indicating that adiponectin has …

Advancing reproductive neuroendocrinology through research on the regulation of GnIH and on its diverse actions on reproductive physiology and behavior

K Tsutsui, T Ubuka, K Ukena - Frontiers in Neuroendocrinology, 2022 - Elsevier
The discovery of gonadotropin-inhibitory hormone (GnIH) in 2000 has led to a new research
era of reproductive neuroendocrinology because, for a long time, researchers believed that …

[HTML][HTML] Contribution of GnIH research to the progress of reproductive neuroendocrinology

K Tsutsui, T Ubuka, YL Son, GE Bentley… - Frontiers in …, 2015 - frontiersin.org
Since the discovery of gonadotropin-releasing hormone (GnRH) in mammals at the
beginning of the 1970s, it was generally accepted that GnRH is the only hypothalamic …

[HTML][HTML] How to contribute to the progress of neuroendocrinology: discovery of GnIH and progress of GnIH research

K Tsutsui, T Ubuka - Frontiers in endocrinology, 2018 - frontiersin.org
It is essential to discover novel neuropeptides that regulate the functions of pituitary, brain
and peripheral secretory glands for the progress of neuroendocrinology. Gonadotropin …

The distribution of Neuropeptide FF and Neuropeptide VF in central and peripheral tissues and their role in energy homeostasis control

J Koller, H Herzog, L Zhang - Neuropeptides, 2021 - Elsevier
Abstract Neuropeptide FF (NPFF) and Neuropeptide VF (NPVF) are part of the extended
RFamide peptide family characterized by their common arginine (R) and amidated …