Mechanical properties of whole-body soft human tissues: a review

G Singh, A Chanda - Biomedical Materials, 2021 - iopscience.iop.org
The mechanical properties of soft tissues play a key role in studying human injuries and their
mitigation strategies. While such properties are indispensable for computational modelling …

Fifty shades of brain: a review on the mechanical testing and modeling of brain tissue

S Budday, TC Ovaert, GA Holzapfel… - … Methods in Engineering, 2020 - Springer
Brain tissue is not only one of the most important but also the most complex and compliant
tissue in the human body. While long underestimated, increasing evidence confirms that …

Mechanical characterization of human brain tissue

S Budday, G Sommer, C Birkl, C Langkammer… - Acta biomaterialia, 2017 - Elsevier
Mechanics are increasingly recognized to play an important role in modulating brain form
and function. Computational simulations are a powerful tool to predict the mechanical …

Mechanical properties of gray and white matter brain tissue by indentation

S Budday, R Nay, R De Rooij, P Steinmann… - Journal of the …, 2015 - Elsevier
The mammalian brain is composed of an outer layer of gray matter, consisting of cell bodies,
dendrites, and unmyelinated axons, and an inner core of white matter, consisting primarily of …

The mechanics of traumatic brain injury: a review of what we know and what we need to know for reducing its societal burden

DF Meaney, B Morrison… - Journal of …, 2014 - asmedigitalcollection.asme.org
Traumatic brain injury (TBI) is a significant public health problem, on pace to become the
third leading cause of death worldwide by 2020. Moreover, emerging evidence linking …

Fifty years of brain tissue mechanical testing: from in vitro to in vivo investigations

S Chatelin, A Constantinesco, R Willinger - Biorheology, 2010 - content.iospress.com
Beginning in the 1960s many studies have been performed to investigate the mechanical
properties of brain. In this paper we point out the difficulties linked with in vitro experimental …

[HTML][HTML] A family of hyperelastic models for human brain tissue

LA Mihai, S Budday, GA Holzapfel, E Kuhl… - Journal of the Mechanics …, 2017 - Elsevier
Experiments on brain samples under multiaxial loading have shown that human brain tissue
is both extremely soft when compared to other biological tissues and characterized by a …

[HTML][HTML] The role of mechanics during brain development

S Budday, P Steinmann, E Kuhl - Journal of the Mechanics and Physics of …, 2014 - Elsevier
Convolutions are a classical hallmark of most mammalian brains. Brain surface morphology
is often associated with intelligence and closely correlated with neurological dysfunction …

Mechanical characterization of brain tissue in compression at dynamic strain rates

B Rashid, M Destrade, MD Gilchrist - Journal of the mechanical behavior of …, 2012 - Elsevier
Traumatic brain injury (TBI) occurs when local mechanical load exceeds certain tolerance
levels for brain tissue. Extensive research has been done previously for brain matter …

Mechanical characterization of brain tissue in tension at dynamic strain rates

B Rashid, M Destrade, MD Gilchrist - Journal of the mechanical behavior of …, 2014 - Elsevier
Mechanical characterization of brain tissue at high loading velocities is crucial for modeling
Traumatic Brain Injury (TBI). During severe impact conditions, brain tissue experiences …