Background Chronic and/or extreme stress in early life, often referred to as early adversity,
childhood trauma, or early life stress, has been associated with a wide range of adverse …

The hypothalamic-pituitary-adrenal (HPA) axis is involved in the pathophysiology of many
neuropsychiatric disorders. Increased HPA axis activity can be observed during chronic …

Depression is a disabling illness which increases the risk of suicide. The Corona Virus
Disease 2019 (COVID-19) pandemic has led to a rise in fear, anxiety, stress, and depression …

Aberrant metabolism is the root cause of several serious health issues, creating a huge
burden to health and leading to diminished life expectancy. A dysregulated metabolism …

Late-life depression occurring in older adults is common, recurrent, and malignant. It is
characterized by affective symptoms, but also cognitive decline, medical comorbidity, and …

Depression is apparently the most common psychiatric disease among the mood disorders
affecting about 10% of the adult population. The etiology and pathogenesis of depression …

Abstract The Adverse Childhood Experiences (ACEs) studies transformed our
understanding of the true burden of trauma. Notable elements of Felitti and colleagues' …

Major depressive disorder (MDD) is a leading cause of distress, disability, and suicides. As
per the latest WHO report, MDD affects more than 260 million people worldwide. Despite …

Background The COVID-19 pandemic exacerbated an already alarming mental health crisis
on college campuses. Nursing students were uniquely impacted through the loss of clinical …

Geroscience offers a counterpoint to the challenged pursuit of curing diseases of aging, by
focusing on slowing the biological aging process for extended healthspan earlier in life …