Indications and strategy for active surveillance of adult low-risk papillary thyroid microcarcinoma: consensus statements from the Japan Association of Endocrine …

I Sugitani, Y Ito, D Takeuchi, H Nakayama, C Masaki… - Thyroid, 2021 - liebertpub.com
Background: The question of how to manage patients with low-risk papillary thyroid
microcarcinoma (PTMC; T1aN0M0) has recently become an important clinical issue. Two …

Thyroid cancer

ME Cabanillas, DG McFadden, C Durante - The Lancet, 2016 - thelancet.com
Thyroid cancer is the fifth most common cancer in women in the USA, and an estimated over
62 000 new cases occurred in men and women in 2015. The incidence continues to rise …

The American Association of Endocrine Surgeons guidelines for the definitive surgical management of thyroid disease in adults

KN Patel, L Yip, CC Lubitz, EG Grubbs, BS Miller… - Annals of …, 2020 - journals.lww.com
Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …

Papillary thyroid microcarcinoma: time to shift from surgery to active surveillance?

S Leboulleux, RM Tuttle, F Pacini… - The lancet Diabetes & …, 2016 - thelancet.com
The incidence of differentiated thyroid cancer is increasing greatly in high-income countries.
Roughly 50% of this increase is attributable to the identification of intrathyroidal papillary …

Molecular testing for thyroid nodules: the experience at McGill University teaching hospitals in Canada

M Rajab, RJ Payne, VI Forest, M Pusztaszeri - Cancers, 2022 - mdpi.com
Simple Summary The aim of this review is to provide a general overview about the
molecular markers (mutations and alterations) of thyroid cancers, present several molecular …

Early diagnosis of low-risk papillary thyroid cancer results rather in overtreatment than a better survival

J Krajewska, A Kukulska… - Frontiers in …, 2020 - frontiersin.org
We are witnessing a rapid worldwide increase in the incidence of papillary thyroid
carcinoma (PTC) in the last thirty years. Extensive implementation of cancer screening and …

[HTML][HTML] Nomogram for predicting central lymph node metastasis in papillary thyroid microcarcinoma: A retrospective cohort study of 8668 patients

Y Wang, Q Guan, J Xiang - International Journal of Surgery, 2018 - Elsevier
Introduction The status of central lymph node metastasis (CLNM) is crucial to determining
the surgical strategies for papillary thyroid micro carcinoma (PTMC). The objective of the …

The predictive value of coexisting BRAFV600E and TERT promoter mutations on poor outcomes and high tumour aggressiveness in papillary thyroid carcinoma: A …

B Chen, Y Shi, Y Xu, J Zhang - Clinical endocrinology, 2021 - Wiley Online Library
BRAFV600E mutation is highly prevalent in patients with papillary thyroid carcinoma (PTC),
and TERT promoter (TERTp) mutation is strongly associated with cancer‐related mortality …

[HTML][HTML] BRAF V600E status may facilitate decision-making on active surveillance of low-risk papillary thyroid microcarcinoma

KJ Kim, SG Kim, J Tan, X Shen, D Viola, R Elisei… - European Journal of …, 2020 - Elsevier
Introduction Conservative active surveillance has been proposed for low-risk papillary
thyroid microcarcinoma (PTMC), defined as≤ 1.0 cm and lacking clinical aggressive …

Mutational status may supersede tumor size in predicting the presence of aggressive pathologic features in well differentiated thyroid cancer

K Semsar-Kazerooni, GB Morand… - … -Head & Neck …, 2022 - journals.sagepub.com
Background In clinical practice, thyroid tumor size plays a critical role in the staging of
thyroid malignancies and in the selection of nodules that should undergo ultrasound-guided …