Exendin-4 promotes Schwann cell survival/migration and myelination in vitro

S Takaku, M Tsukamoto, N Niimi, H Yako… - International Journal of …, 2021 - mdpi.com
Besides its insulinotropic actions on pancreatic β cells, neuroprotective activities of glucagon-
like peptide-1 (GLP-1) have attracted attention. The efficacy of a GLP-1 receptor (GLP-1R) …

Role of exendin-4 in brain insulin resistance, mitochondrial function, and neurite outgrowth in neurons under palmitic acid-induced oxidative stress

D Jo, G Yoon, J Song - Antioxidants, 2021 - mdpi.com
Glucagon like peptide 1 (GLP-1) is an incretin hormone produced by the gut and brain, and
is currently being used as a therapeutic drug for type 2 diabetes and obesity, suggesting that …

[HTML][HTML] Positive Effects of Adiponectin, BDNF, and GLP-1 on Cortical Neurons Counteracting Palmitic Acid Induced Neurotoxicity

D Jo, SY Ahn, SY Choi, Y Choi, DH Lee… - Clinical Nutrition …, 2024 - ncbi.nlm.nih.gov
The prevalence of metabolic syndrome caused by diets containing excessive fatty acids is
increasing worldwide. Patients with metabolic syndrome exhibit abnormal lipid profiles …

Novel roles of mTORC2 in regulation of insulin secretion by actin filament remodeling

M Blandino-Rosano, JO Scheys… - American Journal …, 2022 - journals.physiology.org
Mammalian target of rapamycin (mTOR) kinase is an essential hub where nutrients and
growth factors converge to control cellular metabolism. mTOR interacts with different …

Glucagon-like peptide-1 receptor controls exocytosis in chromaffin cells by increasing full-fusion events

A Gonzalez-Santana, J Estevez-Herrera, EP Seward… - Cell Reports, 2021 - cell.com
Agonists for glucagon-like-peptide-1 receptor (GLP-1R) are currently used for the treatment
of type 2 diabetes and obesity. Their benefits have been centered on pancreas and …

Exendin-4 and Its Related Peptides

MKK Yap, N Misuan - Handbook of Venoms and Toxins of …, 2021 - taylorfrancis.com
Exendin-4 is a 39-residue incretin-mimetic peptide from the venom of Heloderma suspectum
(Gila monster) and H. horridum (beaded lizard). It is a venom analog of mammalian …