Intracellular pathogens have evolved various efficient molecular armaments to subvert
innate defenses. Cellular ubiquitination, a normal physiological process to maintain …

Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), a leading
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …

Mycobacterium tuberculosis (Mtb), the causative agent of Tuberculosis (TB), remains a
pathogen of great interest on a global scale. This airborne pathogen affects the lungs, where …

Reductive evolution has endowed Mycobacterium tuberculosis (M. tb) with moonlighting in
protein functions. We demonstrate that RipA (Rv1477), a peptidoglycan hydrolase, activates …

Tuberculosis (TB) continues to be the leading cause of death by any single infectious agent,
accounting for around 1.7 million annual deaths globally, despite several interventions and …

Autophagy is an ubiquitous homeostatic pathway in mammalian cells and plays a significant
role in host immunity. Substantial evidence indicates that the ability of Mycobacterium …

To the PE_PGRS protein subfamily belongs a group of surface-exposed mycobacterial
antigens that in Mycobacterium tuberculosis (Mtb) H37Rv accounts to more than 65 genes …

The pe/ppe genes are found in pathogenic, slow-growing Mycobacterium tuberculosis and
other M. tuberculosis complex (MTBC) species. These genes are considered key factors in …

The PE/PPE protein family commonly exists in pathogenic species, such as Mycobacterium
tuberculosis, suggesting a role in virulence and its maintenance. However, the exact role of …

Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis
(Mtb), and its incidence and mortality are increasing. The BCG vaccine was developed in the …