Rationale for adjunctive treatment targeting multiple mechanisms in schizophrenia
BJ Kinon, S Leucht, C Tamminga, A Breier… - The Journal of …, 2024 - psychiatrist.com
Importance: Schizophrenia is a complex syndrome with taxing symptoms and for which
treatment challenges remain. Current dopamine D 2 receptor–blocking antipsychotics have …
treatment challenges remain. Current dopamine D 2 receptor–blocking antipsychotics have …
Weight gain and metabolic changes in patients with first-episode psychosis or early-phase schizophrenia treated with olanzapine: a meta-analysis
CU Correll, M Højlund, C Graham… - International Journal …, 2023 - academic.oup.com
Background Patients with first-episode psychosis or early-phase schizophrenia are
susceptible to olanzapine-associated weight gain and cardiometabolic dysregulation. This …
susceptible to olanzapine-associated weight gain and cardiometabolic dysregulation. This …
Sexual dysfunction in schizophrenia: a systematic review and meta-analysis
T Korchia, V Achour, M Faugere, A Albeash… - JAMA …, 2023 - jamanetwork.com
Importance In individuals with schizophrenia, antipsychotic-induced dysfunctions are
frequent but often underexplored in clinical practice. Objective To synthetize the data of …
frequent but often underexplored in clinical practice. Objective To synthetize the data of …
An analysis of views about supported reduction or discontinuation of antipsychotic treatment among people with schizophrenia and other psychotic disorders
Background Antipsychotic medication can reduce psychotic symptoms and risk of relapse in
people with schizophrenia and related disorders, but it is not always effective and adverse …
people with schizophrenia and related disorders, but it is not always effective and adverse …
Weight gain and comorbidities associated with oral second-generation antipsychotics: analysis of real-world data for patients with schizophrenia or bipolar I disorder
MJ Doane, L Bessonova, HS Friedler, KM Mortimer… - BMC psychiatry, 2022 - Springer
Background Many second-generation antipsychotics (SGAs) are associated with weight
gain and cardiometabolic effects. Antipsychotic-associated weight gain is linked to treatment …
gain and cardiometabolic effects. Antipsychotic-associated weight gain is linked to treatment …
A new treatment paradigm: targeting trace amine-associated receptor 1 (TAAR1) in schizophrenia
JM Kane - Journal of Clinical Psychopharmacology, 2022 - journals.lww.com
This continuing education supplement is jointly provided by Medical Education Resources
and CMEology. The supplement is supported by an independent educational grant from …
and CMEology. The supplement is supported by an independent educational grant from …
The impact of weight gain on antipsychotic nonadherence or discontinuation: A systematic review and meta‐analysis
R De, ECC Smith, J Navagnanavel, E Au… - Acta Psychiatrica …, 2024 - Wiley Online Library
Background Nonadherence/discontinuation of antipsychotic (AP) medications represents an
important clinical issue in patients across psychiatric disorders, including schizophrenia …
important clinical issue in patients across psychiatric disorders, including schizophrenia …
The role of pharmacists in supporting service users to optimise antipsychotic medication
Pharmacists have a contribution to make in improving optimising medication use for people
on antipsychotic medication. The rates of prescribing antipsychotics have increased in …
on antipsychotic medication. The rates of prescribing antipsychotics have increased in …
Unmet needs with antipsychotic treatment in schizophrenia and bipolar I disorder: patient perspectives from qualitative focus groups
MJ Doane, K Raymond, C Saucier, L Bessonova… - BMC psychiatry, 2023 - Springer
Background Schizophrenia (SZ) and bipolar I disorder (BD-I) are chronic mental health
disorders often treated with antipsychotic medications. This qualitative study sought to better …
disorders often treated with antipsychotic medications. This qualitative study sought to better …
Aripiprazole 2-month ready-to-use 960 mg (Ari 2MRTU): review of its possible role in schizophrenia therapy
BT Baune - Current Medical Research and Opinion, 2024 - Taylor & Francis
Most patients with schizophrenia need life-long treatment. There is therefore a continued
need for effective and tolerable treatment options. A 2-monthly LAI formulation of …
need for effective and tolerable treatment options. A 2-monthly LAI formulation of …