Our understanding of metabolism is undergoing a dramatic shift. Indeed, the efforts made
towards elucidating the mechanisms controlling the major regulatory pathways are now …

The renin–angiotensin system (RAS) is a complex network that regulates blood pressure,
electrolyte and fluid homeostasis, as well as the function of several organs. Angiotensin …

Tissues within an organism and even cell types within a tissue can age with different
velocities. However, it is unclear whether cells of one type experience different aging …

ToppCluster is a web server application that leverages a powerful enrichment analysis and
underlying data environment for comparative analyses of multiple gene lists. It generates …

Of all of the epithelial ovarian cancers, clear cell carcinoma (CCC) of the ovary has the worst
prognosis. We applied the oligonucleotide array technique to identify genes generally …

The worldwide prevalence of diabetes mellitus and obesity is rapidly increasing not only in
adults but also in children and adolescents. Diabetes is associated with macrovascular …

The subcellular distribution of steroidogenic enzymes has so far been studied mostly in
classical endocrine glands and in the placenta. In the peripheral intracrine organs which …

The distinction of ovarian clear cell carcinomas (CCCs) from high-grade serous carcinomas
(HG-SCs) is sometimes a diagnostic challenge. With the recognition that CCCs respond …

Clear cell tumors of the ovary are frequently associated with ovarian endometriosis.
Clinicopathologically, it has been suggested that clear cell tumors develop from …

Hepatocyte nuclear factor–1β (HNF-1β) is a Pit-1, Oct-1/2, UNC-86 (POU)/homeodomain-
containing transcription factor that regulates tissue-specific gene expression in the liver …