Molecular biomarkers and cognitive impairment in multiple sclerosis: state of the field, limitations, and future direction–a systematic review and meta-analysis

TD Rademacher, SG Meuth, H Wiendl, A Johnen… - Neuroscience & …, 2023 - Elsevier
Objective Multiple sclerosis (MS) is associated with cognitive impairment (CI) such as
slowed information processing speed (IPS). Currently, no immunocellular or molecular …

[HTML][HTML] The role of Tau beyond Alzheimer's disease: a narrative review

E Virgilio, F De Marchi, E Contaldi, U Dianzani… - Biomedicines, 2022 - mdpi.com
Nowadays, there is a need for reliable fluid biomarkers to improve differential diagnosis,
prognosis, and the prediction of treatment response, particularly in the management of …

[HTML][HTML] Using personalized prognosis in the treatment of relapsing multiple sclerosis: A practical guide

B Van Wijmeersch, HP Hartung, P Vermersch… - Frontiers in …, 2022 - frontiersin.org
The clinical course of multiple sclerosis (MS) is highly variable among patients, thus creating
important challenges for the neurologist to appropriately treat and monitor patient progress …

[HTML][HTML] Low serum 25‑hydroxy-vitamin D levels are associated with cognitive impairment in multiple sclerosis

AL Spiezia, F Falco, A Manganelli, A Carotenuto… - Multiple Sclerosis and …, 2023 - Elsevier
Background Cognitive impairment frequently affects people with multiple sclerosis (MS).
Low vitamin D has been associated with cognitive dysfunction in different …

[HTML][HTML] Early predictors of disability and cognition in multiple sclerosis patients: a long-term retrospective analysis

E Virgilio, D Vecchio, MF Sarnelli, V Solara… - Journal of Clinical …, 2023 - mdpi.com
We conducted a retrospective analysis on multiple sclerosis (MS) patients with perceived
cognitive decline and long disease duration to investigate early predictors of future cognitive …

[HTML][HTML] Personalized Nutritional Intervention to Improve Mediterranean Diet Adherence in Female Patients with Multiple Sclerosis: A Randomized Controlled Study

P Papandreou, A Gioxari, E Daskalou, A Vasilopoulou… - Dietetics, 2022 - mdpi.com
Background: Multiple sclerosis (MS) is a chronic immune-mediated central nervous system
disorder that affects females twice as often as males. MS patients show increased …

Association of vitamin D receptor polymorphisms with vitamin D and calcium levels in Turkish multiple sclerosis patients

A Elkama, G Orhan, B Karahalil - Neurodegenerative Disease …, 2022 - Taylor & Francis
Aim: The present study was conducted to assess the impact of gene (vitamin D receptor
[VDR] polymorphisms)–environment (serum vitamin D and calcium levels) interaction on …

[HTML][HTML] Molecular biomarkers and cognitive impairment in multiple sclerosis: A review

S Esmaeili, AZ Obeidat, A Zabeti - Biomarkers in Neuropsychiatry, 2023 - Elsevier
Cognitive Impairment (CI) is one of the most common and devastating manifestations in
patients with Multiple Sclerosis (MS), which directly impacts the quality of life (QOL) and …

[HTML][HTML] Risk Factors for Cognitive Impairment in Multiple Sclerosis Patients

TG Schreiner, I Mihoc, E Grigore, OD Schreiner - Sclerosis, 2024 - mdpi.com
Cognitive impairment is one of the most significant burdens among the many neurological
complaints in multiple sclerosis patients. Cognitive deficits negatively impact these patients' …

[HTML][HTML] Potential role of vitamin D levels in amyotrophic lateral sclerosis cognitive impairment

F De Marchi, M Saraceno, MF Sarnelli, E Virgilio… - Neurological …, 2023 - Springer
Cognitive impairment (CI) is common in amyotrophic lateral sclerosis (ALS): a keystone is
identifying factors that could potentially modify the CI course. In recent years, vitamin D is …