Metabolomics and exposomics are important in the studies of human health and diseases.
Chemical isotope labeling (CIL) combined with mass spectrometry (MS) can not only …

Chemical derivatization-based liquid chromatography-electrospray ionization-mass
spectrometry (LC-ESI-MS) technique is an effective analytical tool for trace small-molecular …

Untargeted methods are typically used in the detection and discovery of small organic
compounds in metabolomics research, and ultra-high-performance liquid chromatography …

Background Vascular calcification is a major cause of the high morbidity and mortality of
cardiovascular diseases and is closely associated with the intestinal microbiota. Short-chain …

Fatty acid esters of hydroxy fatty acids (FAHFAs) are a new class of lipid mediators with
promising anti-diabetic and anti-inflammatory properties. Comprehensive screening and …

Lipids, serving as the structural components of cellular membranes, energy storage, and
signaling molecules, play the essential and multiple roles in biological functions of …

Free fatty acids (FFAs) are vitally important components of lipids that modulate biological
metabolism in various ways. Although the molecular structures are simple, the analysis of …

Bile acids (BAs) are a class of vital gut microbiota-host cometabolites, and they play an
important role in maintaining gut microbiota-host metabolic homeostasis. Very recently, a …

The inclusion of preliminary chemical labeling (derivatization) in the analysis process by
such powerful and widespread methods as electrospray ionization (ESI) and matrix-assisted …

The diagnosis of bladder cancer (BC) is currently based on cystoscopy, which is invasive
and expensive. Here, we describe a noninvasive profiling method for carbonyl metabolic …