α-Keto acids: acylating agents in organic synthesis
A significant number of important acyl-transfer reactions, such as direct acylation, ortho
acylation, heteroatom acylation, and a diversity of cyclization reactions using the title …
acylation, heteroatom acylation, and a diversity of cyclization reactions using the title …
β-Carboline-based molecular hybrids as anticancer agents: A brief sketch
JP Soni, Y Yeole, N Shankaraiah - RSC Medicinal Chemistry, 2021 - pubs.rsc.org
Cancer is a huge burden on the healthcare system and is foremost cause of mortality across
the globe. Among various therapeutic strategies, chemotherapy plays an enormous role in …
the globe. Among various therapeutic strategies, chemotherapy plays an enormous role in …
Metal complexes of β-carboline: Advances in anticancer therapeutics
The platinum-based complexes were the first anticancer metallotherapeutics to emerge and
since their discovery several other coordination compounds consisting of transition metal …
since their discovery several other coordination compounds consisting of transition metal …
[HTML][HTML] Heteroleptic Oxidovanadium(V) Complexes with Activity against Infective and Non-Infective Stages of Trypanosoma cruzi
Five heteroleptic compounds,[VVO (IN-2H)(LH)], where L are 8-hydroxyquinoline derivatives
and IN is a Schiff base ligand, were synthesized and characterized in both the solid and …
and IN is a Schiff base ligand, were synthesized and characterized in both the solid and …
[HTML][HTML] Synthesis, characterization and biological application of four novel metal-Schiff base complexes derived from allylamine and their interactions with human …
Novel metal-based drug candidate including VOL 2, NiL 2, CuL 2 and PdL 2 have been
synthesized from 2-hydroxy-1-allyliminomethyl-naphthalen ligand and have been …
synthesized from 2-hydroxy-1-allyliminomethyl-naphthalen ligand and have been …
New acridine thiourea gold (I) anticancer agents: Targeting the nucleus and inhibiting vasculogenic mimicry
SA Perez, C de Haro, C Vicente, A Donaire… - ACS Chemical …, 2017 - ACS Publications
Two new 1-acridin-9-yl-3-methylthiourea Au (I) DNA intercalators [Au (ACRTU) 2] Cl (2) and
[Au (ACRTU)(PPh3)] PF6 (3) have been prepared. Both complexes were highly active in the …
[Au (ACRTU)(PPh3)] PF6 (3) have been prepared. Both complexes were highly active in the …
Synthesis, antitumor evaluation, and molecular docking studies of indole–indazolyl hydrazide–hydrazone derivatives
A series of ten novel hydrazide–hydrazones linked indole and indazole moieties were
designed and synthesized. All the synthesized compounds were evaluated for their …
designed and synthesized. All the synthesized compounds were evaluated for their …
1 (3)‐Formyl‐β‐carbolines: Potential Aldo‐X Precursors for the Synthesis of β‐Carboline‐Based Molecular Architectures
Abstract β‐Carboline, a privileged scaffold in the alkaloid family, has a broad spectrum of
medicinal properties and is found in several commercial drugs, such as tadalafil …
medicinal properties and is found in several commercial drugs, such as tadalafil …
Indole alkaloids, synthetic dimers and hybrids with potential in vivo anticancer activity
F Song, Y Bian, J Liu, Z Li, L Zhao… - Current Topics in …, 2021 - ingentaconnect.com
Indole, a heterocyclic organic compound, is one of the most promising heterocycles found in
natural and synthetic sources since its derivatives possess fascinating structural diversity …
natural and synthetic sources since its derivatives possess fascinating structural diversity …
Post‐Pictet‐Spengler Cyclization (PPSC): A Strategy to Synthesize Polycyclic β‐Carboline‐Derived Natural Products and Biologically Active N‐Heterocycles
Pictet‐Spengler reaction is a typical condensation reaction of β‐arylethylamine or
Tryptamine with an aldehyde or ketone followed by ring closure to generate …
Tryptamine with an aldehyde or ketone followed by ring closure to generate …