Abstract miR-16-5p is microRNA with important roles in the development of diverse
malignancies including neuroblastoma, osteosarcoma, hepatocellular carcinoma, cervical …

Abstract MiR-16-5p, a member of the miR-16 family, has been reported to be abnormal
expression in tumor tissues and blood of tumor patients, and also downregulated in most …

Trimethylamine-N-oxide (TMAO), an important gut microbiota (GM)-derived metabolite, has
been shown to be abnormally increased in osteoporosis. However, the role and underlying …

Long non-coding RNA (LncRNA) small nucleolar RNA host gene 1 (SNHG1) has been
reported in the occurrence and development of several diseases, but its biological role and …

MiR-16-5p regulates postmenopausal osteoporosis by directly targeting VEGFA - PMC Back
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OBJECTIVE: The aim of this study was to investigate the role of miR-16-5p in hepatocellular
carcinoma (HCC), and to explore the possible underlying mechanism. PATIENTS AND …

Osteoporosis (OP) is a systemic bone disease caused by an imbalance in osteogenesis and
osteoclastic resorption. Extracellular vesicles (EVs)-encapsulated miRNAs from bone …

In the past, different human disorders were described by scientists from the perspective of
either environmental factors or just by genetically related mechanisms. The rise in …

Background LncRNAs have recently emerged as vital regulators in the pathogenesis and
development of various cancers. LncRNA PVT1 is reported to function as an oncogene in …

Background MicroRNAs are known to regulate carcinogenesis of osteosarcoma. Although,
miR-16-5p is known to exert inhibitory effects on several forms of cancers, its effects on the …