Neurological disorders are becoming a growing burden as society ages, and there is a
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …

Nowadays, biomaterials have evolved from the inert supports or functional substitutes to the
bioactive materials able to trigger or promote the regenerative potential of tissues. The …

Mesenchymal stem cells (MSCs) are on the cusp of regenerative medicine due to their
differentiation capacity, favorable culture conditions, ability to be manipulated in vitro, and …

Functional neural competence and integrity require interactive exchanges among sensory
and motor neurons, interneurons and glial cells. Recent studies have attributed some of the …

Mesenchymal stromal cells (MSCs) are currently being investigated for use in a wide variety
of clinical applications. For most of these applications, systemic delivery of the cells is …

Background Inspired by nature, the biomimetic approach has been incorporated into drug
nanocarriers for cancer targeted chemotherapy. The nanocarriers are cloaked in cell …

The use of messenger RNA (mRNA) in gene therapy is increasing in recent years, due to its
unique features compared to plasmid DNA: Transient expression, no need to enter into the …

Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …

Inflammation is ubiquitous in the body, triggering desirable immune response to defend
against dangerous signals or instigating undesirable damage to cells and tissues to cause …

Cell-based therapies have the potential to revolutionize current treatments for diseases with
high prevalence and related economic and social burden. Unfortunately, clinical trials have …