Endothelial-to-mesenchymal transition: cytokine-mediated pathways that determine endothelial fibrosis under inflammatory conditions

L Pérez, N Muñoz-Durango, CA Riedel… - Cytokine & growth factor …, 2017 - Elsevier
During the last decade, the endothelial-to-mesenchymal transition (EndMT) process has
attracted considerable attention due to associations with the onset of certain diseases, such …

Endothelial‐to‐mesenchymal transition in cardiovascular diseases: developmental signaling pathways gone awry

G Sánchez‐Duffhues… - Developmental …, 2018 - Wiley Online Library
The process named endothelial‐to‐mesenchymal transition (EndMT) was observed for the
first time during the development of the chicken embryo several decades ago. Of interest …

Endothelial-to-mesenchymal transition in pulmonary hypertension

B Ranchoux, F Antigny, C Rucker-Martin, A Hautefort… - Circulation, 2015 - Am Heart Assoc
Background—The vascular remodeling responsible for pulmonary arterial hypertension
(PAH) involves predominantly the accumulation of α-smooth muscle actin–expressing …

Fibrotic scar in CNS injuries: from the cellular origins of fibroblasts to the molecular processes of fibrotic scar formation

M Ayazi, S Zivkovic, G Hammel, B Stefanovic, Y Ren - Cells, 2022 - mdpi.com
Central nervous system (CNS) trauma activates a persistent repair response that leads to
fibrotic scar formation within the lesion. This scarring is similar to other organ fibrosis in …

Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors

JF Islas, Y Liu, KC Weng… - Proceedings of the …, 2012 - National Acad Sciences
Unique insights for the reprograming of cell lineages have come from embryonic
development in the ascidian Ciona, which is dependent upon the transcription factors Ci …

TGF-β and BMPR2 signaling in PAH: two black sheep in one family

N Rol, KB Kurakula, C Happé, HJ Bogaard… - International journal of …, 2018 - mdpi.com
Knowledge pertaining to the involvement of transforming growth factor β (TGF-β) and bone
morphogenetic protein (BMP) signaling in pulmonary arterial hypertension (PAH) is …

MALAT1 modulates TGF-β1-induced endothelial-to-mesenchymal transition through downregulation of miR-145

Y Xiang, Y Zhang, Y Tang, Q Li - Cellular physiology and biochemistry, 2017 - karger.com
Abstract Background/Aims: Endothelial-to-mesenchymal transition (EndMT) plays significant
roles under various pathological conditions including cardiovascular diseases, fibrosis, and …

[HTML][HTML] Endothelial progenitor cells in atherosclerosis

F Du, J Zhou, R Gong, X Huang… - … in bioscience: a …, 2012 - ncbi.nlm.nih.gov
Endothelial progenitor cells (EPCs) are involved in the maintenance of endothelial
homoeostasis and in the process of new vessel formation. Experimental and clinical studies …

The role of endothelial-to-mesenchymal transition in cardiovascular disease

Q Peng, D Shan, K Cui, K Li, B Zhu, H Wu, B Wang… - Cells, 2022 - mdpi.com
Endothelial-to-mesenchymal transition (EndoMT) is the process of endothelial cells
progressively losing endothelial-specific markers and gaining mesenchymal phenotypes. In …

[HTML][HTML] Construction of tissue-engineered vascular grafts with enhanced patency by integrating heparin, cell-adhesive peptide, and carbon monoxide nanogenerators …

Y Fan, J Pei, Y Qin, H Du, X Qu, W Li, B Huang, J Tan… - Bioactive Materials, 2024 - Elsevier
Small-diameter tissue-engineered vascular grafts (sdTEVGs) have garnered significant
attention as a potential treatment modality for vascular bypass grafting and replacement …