Urinary Tract Infections Caused by Uropathogenic Escherichia coli: Mechanisms of Infection and Treatment Options

Y Zhou, Z Zhou, L Zheng, Z Gong, Y Li, Y Jin… - International journal of …, 2023 - mdpi.com
Urinary tract infections (UTIs) are common bacterial infections that represent a severe public
health problem. They are often caused by Escherichia coli (E. coli), Klebsiella pneumoniae …

Combination of whole genome sequencing and metagenomics for microbiological diagnostics

S Purushothaman, M Meola, A Egli - International journal of molecular …, 2022 - mdpi.com
Whole genome sequencing (WGS) provides the highest resolution for genome-based
species identification and can provide insight into the antimicrobial resistance and virulence …

Infant gut strain persistence is associated with maternal origin, phylogeny, and traits including surface adhesion and iron acquisition

YC Lou, MR Olm, S Diamond, A Crits-Christoph… - Cell Reports …, 2021 - cell.com
Gut microbiome succession affects infant development. However, it remains unclear what
factors promote persistence of initial bacterial colonizers in the developing gut. Here, we …

[HTML][HTML] The urinary microbiome and biological therapeutics: Novel therapies for urinary tract infections

C Kenneally, CP Murphy, RD Sleator… - Microbiological …, 2022 - Elsevier
The discovery of microbial communities in the urinary tract (the urobiome) has fundamentally
altered the previous doctrine regarding urine sterility and associated urinary disorders …

A one-year genomic investigation of Escherichia coli epidemiology and nosocomial spread at a large US healthcare network

EG Mills, MJ Martin, TL Luo, AC Ong, R Maybank… - Genome medicine, 2022 - Springer
Abstract Background Extra-intestinal pathogenic Escherichia coli (ExPEC) are a leading
cause of bloodstream and urinary tract infections worldwide. Over the last two decades …

Genome wide association study of Escherichia coli bloodstream infection isolates identifies genetic determinants for the portal of entry but not fatal outcome

E Denamur, B Condamine, M Esposito-Farese… - PLoS …, 2022 - journals.plos.org
Escherichia coli is an important cause of bloodstream infections (BSI), which is of concern
given its high mortality and increasing worldwide prevalence. Finding bacterial genetic …

Phylogroup stability contrasts with high within sequence type complex dynamics of Escherichia coli bloodstream infection isolates over a 12-year period

G Royer, MM Darty, O Clermont, B Condamine… - Genome Medicine, 2021 - Springer
Background Escherichia coli is the leading cause of bloodstream infections, associated with
a significant mortality. Recent genomic analyses revealed that few clonal lineages are …

Bacterial genome-wide association study substantiates papGII of Escherichia coli as a major risk factor for urosepsis

A Cuénod, J Agnetti, HMB Seth-Smith, T Roloff… - Genome Medicine, 2023 - Springer
Abstract Background Urinary tract infections (UTIs) are among the most common bacterial
infections worldwide, often caused by uropathogenic Escherichia coli. Multiple bacterial …

Uropathogenic Escherichia coli in Mexico, an overview of virulence and resistance determinants: Systematic review and meta-analysis

MG Ballesteros-Monrreal, P Mendez-Pfeiffer… - Archives of Medical …, 2023 - Elsevier
Background Urinary tract infections (UTI) are one of the most common pathologies in Mexico
and the majority are caused by uropathogenic Escherichia coli (UPEC). UPEC possesses …

[HTML][HTML] Dissemination of ESBL-producing E. coli ST131 through wastewater and environmental water in Switzerland

M Biggel, S Hoehn, A Frei, K Dassler, C Jans… - Environmental …, 2023 - Elsevier
The E. coli lineage ST131 is a major cause of multidrug-resistant urinary tract and
bloodstream infections worldwide. Recently emerged ST131 sublineages spread globally …