Although astrogliosis and microglia activation are characteristic features of multiple sclerosis
(MS) and other central nervous system (CNS) lesions the exact functions of these events are …

The present review is focused on the cell lineage relationships underlying gliogenesis in the
cerebral cortex. Studies conducted both in vivo and in vitro suggest that the process of …

To investigate the role of microRNAs in regulating oligodendrocyte (OL) differentiation and
myelination, we utilized transgenic mice in which microRNA processing was disrupted in OL …

Nervous system development involves a coordinated series of events, including regulation
of cell proliferation and differentiation by specific extracellular factors. S100 beta is a …

We present evidence for unique localization and specific biological activities for transforming
growth factor-βs (TGF-βs) 2 and 3, as compared to TGF-β1, in the nervous system of the 12 …

The distribution of transforming growth factor-beta isoforms 1, 2 and 3 and transforming
growth factor-beta 2 and 3 mRNAs in adult rat central and peripheral nervous system was …

We have developed an in vitro culture system to study the regulation of proliferation and
differentiation of neural precursor cells contained within the neuroepithelium of embruonic …

Oligodendrocyte precursor cells (OPCs) originate in specific areas of the developing central
nervous system (CNS). Once generated, they migrate towards their destinations where they …

Over a century ago, hypertrophy of astrocytes was noted as a pathology of multiple sclerosis
(MS) and was hypothesized to play an important role in this disease, yet the contribution of …

The present study investigates the presence of vitamin D receptor (VDR) in cells of the rat
oligodendrocyte (OL) lineage. VDR transcripts were detected by in situ hybridization in a …