Mapping the Intersubunit Interdomain FMN-Heme Interactions in Neuronal Nitric Oxide Synthase by Targeted Quantitative Cross-Linking Mass Spectrometry

T Jiang, G Wan, H Zhang, YP Gyawali… - Biochemistry, 2024 - ACS Publications
Nitric oxide synthase (NOS) in mammals is a family of multidomain proteins in which
interdomain electron transfer (IET) is controlled by domain–domain interactions. Calmodulin …

[HTML][HTML] A proteome-wide quantitative platform for nanoscale spatially resolved extraction of membrane proteins into native nanodiscs

C Brown, S Ghosh, R McAllister, M Kumar, G Walker… - bioRxiv, 2024 - ncbi.nlm.nih.gov
The intricate molecular environment of the native membrane profoundly influences every
aspect of membrane protein (MP) biology. Despite this, the most prevalent method of …

Functionally Validated Proteome-Wide Bioinformatic Annotation of the Monotopic Phosphoglycosyl Transferase Family

T Durand, GJ Dodge, RP Siuda, HR Higinbotham… - bioRxiv, 2024 - biorxiv.org
Phosphoglycosyl transferases (PGTs) are membrane proteins that initiate glycoconjugate
biosynthesis by transferring a phospho-sugar moiety from a soluble nucleoside diphosphate …