NLRP3 inflammasome in diabetic cardiomyopathy and exercise intervention

Y Sun, S Ding - International journal of molecular sciences, 2021 - mdpi.com
Diabetic cardiomyopathy (DCM), as a common complication of diabetes, is characterized by
chronic low-grade inflammation. The NLRP3 inflammasome is a key sensor mediating …

Exercise mitigates age-related metabolic diseases by improving mitochondrial dysfunction

D Jia, Z Tian, R Wang - Ageing Research Reviews, 2023 - Elsevier
The benefits of regular physical activity are related to delaying and reversing the onset of
ageing and age-related disorders, including cardiomyopathy, neurodegenerative diseases …

[HTML][HTML] Activation of NRF2/FPN1 pathway attenuates myocardial ischemia–reperfusion injury in diabetic rats by regulating iron homeostasis and ferroptosis

H Tian, Y Xiong, Y Zhang, Y Leng, J Tao, L Li… - Cell Stress and …, 2022 - Elsevier
In patients with ischemic heart disease, myocardial ischemia–reperfusion injury (IRI) can
aggravate their condition even worse, and diabetes increases their risk of myocardial IRI …

Physical activity/inactivity and COVID-19

A Crisafulli, P Pagliaro - European journal of preventive …, 2021 - academic.oup.com
The pandemic coronavirus disease (COVID-19) caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus has spread globally impacting health and …

Glucose transporters in cardiovascular system in health and disease

L Bertrand, J Auquier, E Renguet, M Angé… - … -European Journal of …, 2020 - Springer
Glucose transporters are essential for the heart to sustain its function. Due to its nature as a
high energy-consuming organ, the heart needs to catabolize a huge quantity of metabolic …

Mortality trend analysis of ischemic heart disease in China between 2010 and 2019: a joinpoint analysis

X Fu, J Wang, S Jiang, J Wu, Z Mu, Y Tang, S Wang… - BMC public health, 2023 - Springer
Background This study presented the mortality trend of ischemic heart disease (IHD) in
Chinese residents from 2010 to 2019 and provided a basis for further establishment of …

Melatonin ameliorates myocardial infarction in obese diabetic individuals: the possible involvement of macrophage apoptotic factors

J Maity, T Dey, A Banerjee… - Journal of Pineal …, 2023 - Wiley Online Library
In recent days, the hike in obesity‐mediated epidemics across the globe and the prevalence
of obesity‐induced cardiovascular disease has become one of the chief grounds for …

Heart failure in diabetes

SS Jankauskas, U Kansakar, F Varzideh, S Wilson… - Metabolism, 2021 - Elsevier
Heart failure and cardiovascular disorders represent the leading cause of death in diabetic
patients. Here we present a systematic review of the main mechanisms underlying the …

[HTML][HTML] Why does type 2 diabetes mellitus impair weight reduction in patients with obesity? A review

HE Bays - Obesity Pillars, 2023 - Elsevier
Background A common adiposopathic complication of obesity is type 2 diabetes mellitus.
Healthful weight reduction in patients with obesity can improve glucose metabolism and …

Preclinical multi-target strategies for myocardial ischemia-reperfusion injury

Y Li, Y Gao, G Li - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Despite promising breakthroughs in diagnosing and treating acute coronary syndromes,
cardiovascular disease's high global mortality rate remains indisputable. Nearly half of these …