[HTML][HTML] Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches
The site-specific delivery of antitumor agents is of importance for providing effective cancer
suppression. Poor bioavailability of anticancer compounds and the presence of biological …
suppression. Poor bioavailability of anticancer compounds and the presence of biological …
The role of microRNA-185 in the pathogenesis of human diseases: a focus on cancer
MicroRNAs (miRNAs) are a widely-studied class of non-coding RNAs characterized by their
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …
[HTML][HTML] From oncolytic peptides to oncolytic polymers: A new paradigm for oncotherapy
H Liu, W Shen, W Liu, Z Yang, D Yin, C Xiao - Bioactive Materials, 2024 - Elsevier
Traditional cancer therapy methods, especially those directed against specific intracellular
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …
[HTML][HTML] Mechanisms and regulation of defensins in host defense
As a family of cationic host defense peptides, defensins are mainly synthesized by Paneth
cells, neutrophils, and epithelial cells, contributing to host defense. Their biological functions …
cells, neutrophils, and epithelial cells, contributing to host defense. Their biological functions …
[HTML][HTML] microRNA-184 in the landscape of human malignancies: a review to roles and clinical significance
MicroRNAs (miRNAs) are a class of non-coding RNAs (ncRNAs) with a short length of 19–
22 nucleotides. miRNAs are posttranscriptional regulators of gene expression involved in …
22 nucleotides. miRNAs are posttranscriptional regulators of gene expression involved in …
Advancement of cell-penetrating peptides in combating triple-negative breast cancer
Extensive research efforts have been made and are still ongoing in the search for an ideal
anti-cancer therapy. Almost all chemotherapeutics require a carrier or vehicle, a drug …
anti-cancer therapy. Almost all chemotherapeutics require a carrier or vehicle, a drug …
[HTML][HTML] Lights and shadows on the therapeutic use of antimicrobial peptides
D Bellotti, M Remelli - Molecules, 2022 - mdpi.com
The emergence of antimicrobial-resistant infections is still a major concern for public health
worldwide. The number of pathogenic microorganisms capable of resisting common …
worldwide. The number of pathogenic microorganisms capable of resisting common …
Current therapeutic approaches and promising perspectives of using bioengineered peptides in fighting chemoresistance in triple-negative breast cancer
Breast cancer is a collation of malignancies that manifest in the mammary glands at the early
stages. Among breast cancer subtypes, triple-negative breast cancer (TNBC) shows the …
stages. Among breast cancer subtypes, triple-negative breast cancer (TNBC) shows the …
[HTML][HTML] Autophagy, a critical element in the aging male reproductive disorders and prostate cancer: a therapeutic point of view
Autophagy is a highly conserved, lysosome-dependent biological mechanism involved in
the degradation and recycling of cellular components. There is growing evidence that …
the degradation and recycling of cellular components. There is growing evidence that …
Spatial distribution control of antimicrobial peptides through a novel polymeric carrier for safe and efficient cancer treatment
Z Kang, C Wang, Z Zhang, Q Liu, Y Zheng… - Advanced …, 2022 - Wiley Online Library
Antimicrobial peptides (AMPs) hold great potential for use in tumor treatment. However,
developing AMP‐based antitumor therapies is challenging due to circulatory instability …
developing AMP‐based antitumor therapies is challenging due to circulatory instability …