Phenotypical and genotypical differences among Leishmania (Leishmania) amazonensis isolates that caused different clinical frames in humans and dogs: A …

TF Silva, F Tomiotto-Pellissier, AKS Pasquali… - Acta Tropica, 2021 - Elsevier
Leishmania (Leishmania) amazonensis is an important etiological agent of American
cutaneous leishmaniasis (ACL) in Brazil. The species causes a large spectrum of clinical …

Assay development in leishmaniasis drug discovery: a comprehensive review

B Zulfiqar, VM Avery - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
Introduction Cutaneous, muco-cutaneous and visceral leishmaniasis occur due to an
infection with the protozoan parasite Leishmania. The current therapeutic options are limited …

[HTML][HTML] Colonization and genetic diversification processes of Leishmania infantum in the Americas

P Schwabl, MC Boité, G Bussotti, A Jacobs… - Communications …, 2021 - nature.com
Leishmania infantum causes visceral leishmaniasis, a deadly vector-borne disease
introduced to the Americas during the colonial era. This non-native trypanosomatid parasite …

Candidates for Balancing Selection in Leishmania donovani Complex Parasites

CA Grace, S Forrester, VC Silva… - Genome biology and …, 2021 - academic.oup.com
The Leishmania donovani species complex is the causative agent of visceral leishmaniasis,
which cause 20–40,000 fatalities a year. Here, we conduct a screen for balancing selection …

Revisiting the heterogeneous global genomic population structure of Leishmania infantum

LH Patino, A Castillo-Castañeda… - Microbial …, 2021 - microbiologyresearch.org
Leishmania infantum is the main causative agent responsible for visceral leishmaniasis
(VL), a disease with global distribution. The genomic structure and genetic variation of this …

[HTML][HTML] Increased levels of cortisol are associated with the severity of experimental visceral leishmaniasis in a Leishmania (L.) infantum-hamster model

TD Barros-Gonçalves, AF Saavedra… - PLoS Neglected …, 2021 - journals.plos.org
Background Several infectious diseases are associated with hypothalamic-pituitary-adrenal
(HPA) axis disorders by elevating circulating glucocorticoids (GCs), which are known to …

[HTML][HTML] Spatial and temporal variability of visceral leishmaniasis in Colombia, 2007 to 2018

A Castillo-Castañeda, G Herrera, MS Ayala… - The American Journal …, 2021 - ncbi.nlm.nih.gov
Visceral leishmaniasis (VL) is a neglected tropical disease associated with poverty and is
endemic in 56 countries worldwide. Brazil, Venezuela, and Colombia are the most affected …

Nuclear and mitochondrial genome sequencing of North-African Leishmania infantum isolates from cured and relapsed visceral leishmaniasis patients reveals …

G Bussotti, A Benkahla, F Jeddi… - Microbial …, 2020 - microbiologyresearch.org
Although several studies have investigated genetic diversity of Leishmania infantum in North
Africa, genome-wide analyses are lacking. Here, we conducted comparative analyses of …

[PDF][PDF] Leishmania infections and Leishmania species in central Europe

E Kniha, H Aspöck, H Auer… - … Monatsschrift Vet Med …, 2023 - researchgate.net
Species of the genus Leishmania (Trypanosomatidae) are parasitic protists that are
transmitted to vertebrates by the bites of female sandflies (Phlebotominae) and are the …

The Parasitemia has Contributed to the Severity of Cases of Visceral Leishmaniasis

CM Campelo, AC Medvedovsky… - Indian Journal of …, 2024 - Springer
Visceral leishmaniasis (VL) occurs due to the evolution, virulence, and adaptation of
Leishmania, vector biology, host immune system evasion, and reservoir hosts. Parasitemia …