Background and aim Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory
disease; the clinical manifestations are correlated with continuum multiarticular synovitis …

Damage to peripheral nerves is a widely extended health problem, causing important
socioeconomic costs worldwide. Indeed, peripheral nerve injuries (PNI) have been …

Macrophages are highly plastic cells that can polarize into functionally distinct subsets in
vivo and in vitro in response to environmental signals. The development of protocols to …

Pancreatic tumors are known to be resistant to immunotherapy due to the extensive immune
suppressive tumor microenvironment (TME). We hypothesized that CXCL12 and PD-L1 are …

Tumor-associated macrophages (TAM) play a controversial role in epithelial–mesenchymal
transition (EMT) and prognosis of colorectal cancer (CRC). In particular, the …

Bladder cancer is one of the most malignant tumors closely associated with macrophages.
Polyporus polysaccharide (PPS) has shown excellent efficacy in treating bladder cancer …

Cryptococcus neoformans is a leading cause of invasive fungal infections among
immunocompromised patients. However, the cellular constituents of the innate immune …

Macrophages play a key role in disseminated cryptococcosis, a deadly fungal disease
caused by Cryptococcus neoformans. This opportunistic infection can arise following the …

Myeloid-derived monocyte and macrophages are key cells in the bone that contribute to
remodeling and injury repair. However, their temporal polarization status and control of bone …

Macrophages serve as a first line of defense against infection with the facultative
intracellular pathogen, Cryptococcus neoformans (Cn). However, the ability of these innate …