Metallothionein 1: A new spotlight on inflammatory diseases

H Dai, L Wang, L Li, Z Huang, L Ye - Frontiers in immunology, 2021 - frontiersin.org
MT1 has been demonstrated to be an essential stress protein in maintaining physiological
balance and regulating immune homeostasis. While the immunological involvement of MT1 …

Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets

B Chen, P Yu, WN Chan, F Xie, Y Zhang… - … and Targeted Therapy, 2024 - nature.com
Zinc metabolism at the cellular level is critical for many biological processes in the body. A
key observation is the disruption of cellular homeostasis, often coinciding with disease …

Omniphobic ZIF‐8@ hydrogel membrane by microfluidic‐emulsion‐templating method for wound healing

X Yao, G Zhu, P Zhu, J Ma, W Chen… - Advanced Functional …, 2020 - Wiley Online Library
Bacterial adhesion and colonization can result in chronic non‐healing wounds. Current
hydrophilic wound dressings can release antibacterial agents into the wound exudate, but …

Machine learning-based characterization of cuprotosis-related biomarkers and immune infiltration in Parkinson's disease

S Zhao, L Zhang, W Ji, Y Shi, G Lai, H Chi… - Frontiers in …, 2022 - frontiersin.org
Background: Parkinson's disease (PD) is a neurodegenerative disease commonly seen in
the elderly. On the other hand, cuprotosis is a new copper-dependent type of cell death that …

Vitamin metal–organic framework-laden microfibers from microfluidics for wound healing

Y Yu, G Chen, J Guo, Y Liu, J Ren, T Kong… - Materials Horizons, 2018 - pubs.rsc.org
Vitamin MOF-laden microfibers with alginate shells and copper-or zinc-vitamin framework
cores are controllably generated by using a coaxial capillary microfluidic spinning approach …

Extracellular Cu2+ pools and their detection: From current knowledge to next-generation probes

E Falcone, M Okafor, N Vitale, L Raibaut, A Sour… - Coordination Chemistry …, 2021 - Elsevier
Copper (Cu) is an essential micronutrient for most organisms and serves mainly as a redox-
active catalytic centre in enzymes cycling between Cu+ and Cu 2+. Membrane transporters …

Antioxidant berberine-derivative inhibits multifaceted amyloid toxicity

K Rajasekhar, S Samanta, V Bagoband, NA Murugan… - Iscience, 2020 - cell.com
Multiple lines of evidence indicate that amyloid beta (Aβ) peptide is responsible for the
pathological devastation caused in Alzheimer's disease (AD). Aβ aggregation species …

Metal binding and interdomain thermodynamics of mammalian metallothionein-3: enthalpically favoured Cu+ supplants entropically favoured Zn 2+ to form Cu 4+ …

MR Mehlenbacher, R Elsiesy, R Lakha… - Chemical …, 2022 - pubs.rsc.org
Metallothioneins (MTs) are a ubiquitous class of small metal-binding proteins involved in
metal homeostasis and detoxification. While known for their high affinity for d10 metal ions …

[HTML][HTML] Advances in aptamers against Aβ and applications in Aβ detection and regulation for Alzheimer's disease

Y Zheng, L Zhang, J Zhao, L Li, M Wang, P Gao… - Theranostics, 2022 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is an irreversible neurodegenerative disease, causing profound
social and economic implications. Early diagnosis and treatment of AD have faced great …

Graphene quantum dots as singlet oxygen producer or radical quencher-The matter of functionalization with urea/thiourea

SP Jovanović, Z Syrgiannis, MD Budimir… - Materials Science and …, 2020 - Elsevier
Due to their low cost and possible green synthesis, high stability and resistance to
photobleaching, graphene quantum dots (GQDs) can be considered as one of the class of …