Supramolecular chemotherapy based on host–guest molecular recognition: a novel strategy in the battle against cancer with a bright future

J Zhou, G Yu, F Huang - Chemical Society Reviews, 2017 - pubs.rsc.org
Chemotherapy is currently one of the most effective ways to treat cancer. However,
traditional chemotherapy faces several obstacles to clinical trials, such as poor …

Recent advances in shear‐thinning and self‐healing hydrogels for biomedical applications

S Uman, A Dhand, JA Burdick - Journal of Applied Polymer …, 2020 - Wiley Online Library
Shear‐thinning and self‐healing hydrogels are being investigated in various biomedical
applications including drug delivery, tissue engineering, and 3D bioprinting. Such hydrogels …

[HTML][HTML] Biomedical applications of supramolecular systems based on host–guest interactions

X Ma, Y Zhao - Chemical reviews, 2015 - ACS Publications
The development of supramolecular chemistry dates back to 1987 when Lehn, Cram, and
Pedersen won the Nobel Prize on account of their leading discoveries in the host–guest …

Applications of cucurbiturils in medicinal chemistry and chemical biology

D Das, KI Assaf, WM Nau - Frontiers in chemistry, 2019 - frontiersin.org
The supramolecular chemistry of cucurbit [n] urils (CB n) has been rapidly developing to
encompass diverse medicinal applications, including drug formulation and delivery …

Targeting and delivery of platinum-based anticancer drugs

X Wang, Z Guo - Chemical Society Reviews, 2013 - pubs.rsc.org
Platinum-based anticancer drugs occupy a crucial role in the treatment of various malignant
tumours. However, the efficacy and applicability of platinum drugs are heavily restricted by …

A chemical perspective on the clinical use of platinum-based anticancer drugs

S Alassadi, MJ Pisani, NJ Wheate - Dalton Transactions, 2022 - pubs.rsc.org
Platinum drugs have been a mainstay of cancer chemotherapy since the introduction of
cisplatin in the 1970s. Since then, carboplatin and oxaliplatin have been approved world …

Host–guest supramolecular nanosystems for cancer diagnostics and therapeutics

L Wang, L Li, Y Fan, H Wang - Advanced Materials, 2013 - Wiley Online Library
Extensive efforts have been devoted to the construction of functional supramolecular
nanosystems for applications in catalysis, energy conversion, sensing and biomedicine. The …

Macrocycles as drug-enhancing excipients in pharmaceutical formulations

A Gu, NJ Wheate - Journal of Inclusion Phenomena and Macrocyclic …, 2021 - Springer
The macrocycle families: cucurbit [n] urils, n-cyclodextrins, calix [n] arenes, and pillar [n]
arenes (where n represents the number of subunits in each homologue) have shown …

Applications of Cucurbit[n]urils (n=7 or 8) in Pharmaceutical Sciences and Complexation of Biomolecules

H Yin, R Wang - Israel Journal of Chemistry, 2018 - Wiley Online Library
Abstract Cucurbit [7] uril (CB [7]) and cucurbit [8] uril (CB [8]) are two key members of the
cucurbit [n] uril (CB [n]) family of macrocycles. Because of the good water solubility of CB [7] …

Androgen control of lipid metabolism in prostate cancer: novel insights and future applications

LM Butler, MM Centenera… - Endocrine-related …, 2016 - erc.bioscientifica.com
The year 2015 marks the 50th anniversary since the discovery of the anticancer potential of
cisplatin and it remains just as useful now as it did back then, especially for the treatment of …