Results The evidence supports that there are a number of biologically plausible
mechanisms whereby physical activity can influence cancer risk, and that physical activity is …

The effectiveness of anticancer drugs in treating a solid tumour is dependent on delivery of
the drug to virtually all cancer cells in the tumour. The distribution of drug in tumour tissue …

Abnormal blood and lymphatic vessels create a hostile tumor microenvironment
characterized by hypoxia, low pH, and elevated interstitial fluid pressure. These …

The benefits of exercise training for cancer patients are becoming increasingly evident.
Physical exercise has been shown to reduce cancer incidence and inhibit tumor growth …

Exercise has a wide range of systemic effects. In animal models, repeated exertion reduces
malignant tumor progression, and clinically, exercise can improve outcome for cancer …

The circadian rhythm is an evolutionarily conserved time-keeping system that comprises a
wide variety of processes including sleep–wake cycles, eating–fasting cycles, and activity …

The integrity and composition of the tumour microenvironment (TME) is highly plastic,
undergoing constant remodelling in response to instructive signals derived from alterations …

Exercise can enhance motivation to change lifestyle behaviors, improve aerobic fitness,
improve physical function, control fatigue, and enhance quality of life. Studies have …

Physical exercise has gradually become a focus in cancer treatment due to its pronounced
role in reducing cancer risk, enhancing therapeutic efficacy, and improving prognosis. In …

Exercise is recognized by clinicians in the field of clinical oncology for its potential role in
reducing the risk of certain cancers and in reducing the risk of disease recurrence and …