Background Cancer patients can achieve dramatic responses to chemotherapy yet retain
resistant tumor cells, which ultimately results in relapse. Although xenograft model studies …

In low‐and middle‐income countries (LMICs), limited resources, suboptimal risk
stratification, and disproportionate patient‐to‐infrastructure ratio result in low survival of …

Background Myelodysplastic syndrome (MDS) is a rare disease in children and the
treatment option before the allogeneic hematopoietic stem cell transplantation (allo-HSCT) …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic affected the
pediatric oncology population globally. Over the course of 2 years, increasing reports have …

Classical r-vs. K-selection theory describes the trade-offs between high reproductive output
and competitiveness and guides research in evolutionary ecology. While its impact has …

Introduction: Acute myeloid leukemia is a challenging disease, due to a poor prognosis in
developing countries. Herein, we aim to describe the clinical characteristics and outcomes …

Paediatric acute myeloid leukaemia (AML) is a heterogeneous disease characterised by the
malignant transformation of myeloid precursor cells with impaired differentiation. Standard …

Abstract Treatment refusal and death as a result of toxicity account for most treatment
failures among children with acute myeloid leukemia (AML) in resource-constrained …

The incidence and spectrum of infections in pediatric leukemia patients vary depending on
the type of leukemia. AML, which involves intensive chemotherapeutic regimes, leads to …

国家自然科学基金委员会重大研究计划“微进化过程的多基因作用机制” 历时9 年于2020
年完成结束评估. 本文概述了该重大研究计划取得的重要研究进展, 包括在微进化机制基本理论 …