Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology
The term 'immunogenic cell death'(ICD) denotes an immunologically unique type of
regulated cell death that enables, rather than suppresses, T cell-driven immune responses …
regulated cell death that enables, rather than suppresses, T cell-driven immune responses …
Trial watch: immunogenic cell death induction by anticancer chemotherapeutics
The expression “immunogenic cell death”(ICD) refers to a functionally unique form of cell
death that facilitates (instead of suppressing) a T cell-dependent immune response specific …
death that facilitates (instead of suppressing) a T cell-dependent immune response specific …
Concepts of GPCR‐controlled navigation in the immune system
T Lämmermann, W Kastenmüller - Immunological reviews, 2019 - Wiley Online Library
G‐protein–coupled receptor (GPCR) signaling is essential for the spatiotemporal control of
leukocyte dynamics during immune responses. For efficient navigation through mammalian …
leukocyte dynamics during immune responses. For efficient navigation through mammalian …
CD8+ T cells and NK cells: parallel and complementary soldiers of immunotherapy
J Rosenberg, J Huang - Current opinion in chemical engineering, 2018 - Elsevier
Highlights•CD8+ T cells and NK cells are both cytotoxic cells with engineering potential.•NK
cells are comparable to CD8+ T cells but far less understood.•Cancer immunotherapies …
cells are comparable to CD8+ T cells but far less understood.•Cancer immunotherapies …
In Vivo T Cell-Targeting Nanoparticle Drug Delivery Systems: Considerations for Rational Design
T cells play an important role in immunity and repair and are implicated in diseases,
including blood cancers, viral infections, and inflammation, making them attractive targets for …
including blood cancers, viral infections, and inflammation, making them attractive targets for …
[HTML][HTML] Human CD8+ CD57- TEMRA cells: Too young to be called "old"
K Verma, J Ogonek, PR Varanasi, S Luther, I Bünting… - PLoS …, 2017 - journals.plos.org
End-stage differentiation of antigen-specific T-cells may precede loss of immune responses
against eg viral infections after allogeneic stem cell transplantation (SCT). Antigen-specific …
against eg viral infections after allogeneic stem cell transplantation (SCT). Antigen-specific …
[HTML][HTML] Simulation modelling for immunologists
The immune system is inordinately complex with many interacting components determining
overall outcomes. Mathematical and computational modelling provides a useful way in …
overall outcomes. Mathematical and computational modelling provides a useful way in …
[HTML][HTML] Host immune response against DENV and ZIKV infections
SD Sekaran, AA Ismail, G Thergarajan… - Frontiers in cellular …, 2022 - frontiersin.org
Dengue is a major public health concern, affecting almost 400 million people worldwide,
with about 70% of the global burden of disease in Asia. Despite revised clinical …
with about 70% of the global burden of disease in Asia. Despite revised clinical …
Malnutrition is associated with hyperinflammation and immunosuppression in COVID‐19 patients: a prospective observational study
H Liu, L Zhou, H Wang, X Wang, G Qu… - Nutrition in Clinical …, 2021 - Wiley Online Library
Background Coronavirus disease 2019 (COVID‐19) is spreading globally and has caused
many deaths. This study investigated, for the first time, COVID‐19 patients' nutrition status …
many deaths. This study investigated, for the first time, COVID‐19 patients' nutrition status …
[HTML][HTML] Consensus cluster analysis of apoptosis-related genes in patients with osteoarthritis and their correlation with immune cell infiltration
E Yu, M Zhang, G Xu, X Liu, J Yan - Frontiers in Immunology, 2023 - frontiersin.org
Background Osteoarthritis (OA) progression involves multiple factors, including cartilage
erosion as the basic pathological mechanism of degeneration, and is closely related to …
erosion as the basic pathological mechanism of degeneration, and is closely related to …