Cardiorenal syndrome: long road between kidney and heart

CVC Junho, M Trentin-Sonoda, K Panico… - Heart failure …, 2022 - Springer
Almost 200 years ago, the first evidence described by Robert Bright (1836) showed the
strong interaction between the kidneys and heart and, since then, the scientific community …

Cardiovascular disease in COVID-19: a systematic review and meta-analysis of 10,898 patients and proposal of a triage risk stratification tool

S Momtazmanesh, P Shobeiri, S Hanaei… - The Egyptian Heart …, 2020 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) pandemic has drastically
affected global health. Despite several studies, there is yet a dearth of data regarding the …

Effects of SGLT2 inhibitors on cardiovascular outcomes in patients with stage 3/4 CKD: A meta-analysis

N Li, G Zhou, Y Zheng, D Lv, X Zhu, P Wei, M Zheng… - PLoS …, 2022 - journals.plos.org
Introduction After stage 3 CKD, the risk of adverse cardiovascular events increased
significantly. Therefore, we performed a meta-analysis to investigate the cardiovascular …

Interleukin-33 mediates cardiomyopathy after acute kidney injury by signaling to cardiomyocytes

N Florens, RK Kasam, V Rudman-Melnick, SC Lin… - Circulation, 2023 - Am Heart Assoc
Background: Acute kidney injury (AKI) is a short-term life-threatening condition that, if
survived, can lead to renal insufficiency and development of chronic kidney disease. The …

A norepinephrine weaning strategy using dynamic arterial elastance is associated with reduction of acute kidney injury in patients with vasoplegia after cardiac …

PG Guinot, P Huette, B Bouhemad, O Abou-Arab… - Journal of Clinical …, 2023 - Elsevier
Study objective To evaluate the impact of a dynamic arterial elastance guided
norepinephrine weaning strategy on the occurrence of acute kidney injury (AKI) in patients …

Guanxining injection alleviates fibrosis in heart failure mice and regulates SLC7A11/GPX4 axis

C Wang, J Zhou, S Wang, Y Liu, K Long, T Sun… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Radix et Rhizoma Salviae Miltiorrhizae (Salvia
miltiorrhiza Bge., Lamiaceae, Danshen in Chinese) and Chuanxiong Rhizoma (rhizomes of …

Diabetic cardiomyopathy: the need for adjusting experimental models to meet clinical reality

F Lezoualc'h, L Badimon, H Baker… - Cardiovascular …, 2023 - academic.oup.com
Diabetic cardiomyopathy (CM), occurring in the absence of hypertension, coronary artery
disease, and valvular or congenital heart disease, is now recognized as a distinct …

Beyond the cardiorenal syndrome: pathophysiological approaches and biomarkers for renal and cardiac crosstalk

ON Buliga-Finis, A Ouatu, MC Badescu, N Dima… - Diagnostics, 2022 - mdpi.com
Cardiorenal syndrome encompasses complex multifactorial facets and carries significant
morbidity and mortality worldwide. The bi-directional relationship between the heart and …

Attenuation of circulating trimethylamine N-oxide prevents the progression of cardiac and renal dysfunction in a rat model of chronic cardiorenal syndrome

D Zou, Y Li, G Sun - Frontiers in Pharmacology, 2021 - frontiersin.org
Chronic heart failure (HF) frequently causes progressive decline in kidney function, known
as cardiorenal syndrome-2 (CRS2). Current treatment options for CRS2 remain …

Role and mechanism of the renin-angiotensin-aldosterone system in the onset and development of cardiorenal syndrome

K Ma, W Gao, H Xu, W Liang… - Journal of the Renin …, 2022 - journals.sagepub.com
Cardiorenal syndrome (CRS), a clinical syndrome involving multiple pathological
mechanisms, exhibits high morbidity and mortality. According to the primary activity of the …