[HTML][HTML] The multifaceted role of glutathione S-transferases in health and disease

AMA Mazari, L Zhang, ZW Ye, J Zhang, KD Tew… - Biomolecules, 2023 - mdpi.com
In humans, the cytosolic glutathione S-transferase (GST) family of proteins is encoded by 16
genes presented in seven different classes. GSTs exhibit remarkable structural similarity …

Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity

K Gupta, G Kaur, T Pathak, I Banerjee - Gene, 2022 - Elsevier
The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …

[HTML][HTML] Glutathione deficiency in the pathogenesis of SARS-CoV-2 infection and its effects upon the host immune response in severe COVID-19 disease

CA Labarrere, GS Kassab - Frontiers in Microbiology, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus
disease 19 (COVID-19) has numerous risk factors leading to severe disease with high …

Brain fog: A narrative review of the most common mysterious cognitive disorder in COVID-19

M Aghajani Mir - Molecular Neurobiology, 2023 - Springer
It has been more than three years since COVID-19 impacted the lives of millions of people,
many of whom suffer from long-term effects known as long-haulers. Notwithstanding …

[HTML][HTML] Distinct transcriptomic profiles in children prior to the appearance of type 1 diabetes-linked islet autoantibodies and following enterovirus infection

J Lin, E Moradi, K Salenius, S Lehtipuro… - Nature …, 2023 - nature.com
Although the genetic basis and pathogenesis of type 1 diabetes have been studied
extensively, how host responses to environmental factors might contribute to autoantibody …

N‐Acetylcysteine and Other Sulfur‐Donors as a Preventative and Adjunct Therapy for COVID‐19

HN du Preez, C Aldous, HG Kruger… - Advances in …, 2022 - Wiley Online Library
The airway epithelial glycocalyx plays an important role in preventing severe acute
respiratory syndrome coronavirus 2 entry into the epithelial cells, while the endothelial …

Host genetic diversity and genetic variations of SARS-CoV-2 in COVID-19 pathogenesis and the effectiveness of vaccination

M Delshad, MJ Sanaei… - International …, 2022 - Elsevier
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), responsible for the
outbreak of coronavirus disease 2019 (COVID-19), has shown a vast range of clinical …

Role of genetic variants and host polymorphisms on COVID‐19: From viral entrance mechanisms to immunological reactions

A Adli, M Rahimi, R Khodaie… - Journal of Medical …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by a highly pathogenic emerging
virus, is called severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Knowledge …

[HTML][HTML] Global human threat: the potential synergism between mercury intoxication and COVID-19

GP Arrifano, M Augusto-Oliveira… - International journal of …, 2023 - mdpi.com
The COVID-19 pandemic affected billions of people worldwide, and exposure to toxic metals
has emerged as an important risk factor for COVID-19 severity. Mercury is currently ranked …

[HTML][HTML] GSTP1 and GSTM3 Variant Alleles Affect Susceptibility and Severity of COVID-19

V Coric, I Milosevic, T Djukic, Z Bukumiric… - Frontiers in Molecular …, 2021 - frontiersin.org
Based on the premise that oxidative stress plays an important role in severe acute
respiratory syndrome coronavirus (SARS-CoV-2) infection, we speculated that variations in …